Expression of fibroblast growth factor receptor in adult mouse utricle damaged by streptomycin sulfate

被引:2
作者
Yamashita, H [1 ]
Gondo, T [1 ]
Ishihara, T [1 ]
Takahashi, M [1 ]
机构
[1] Yamaguchi Univ, Sch Med, Dept Otolaryngol, Yamaguchi 755, Japan
来源
ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES | 1998年 / 60卷 / 01期
关键词
fibroblast growth factor receptor; utricle; synaptic plasticity; confocal laser scanning microscope; inner ear;
D O I
10.1159/000027553
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
The expression of fibroblast growth factor (FGF) receptor was investigated in adult mouse utricles damaged by streptomycin sulfate using confocal laser scanning microscopy (CLSM), The nerve endings in the mouse utricles could be detected by the immunoreactivity of neurofilament by CLSM. In the utricles of control adult mice, little expression of FGF receptor could be detected by a method of double staining for FGF receptor and neurofilament immunoreactivities. However, the expression of FGF immunoreactivity increased in the nerve endings of the damaged utricles. This result suggests that FGF is probably related to the synaptic plasticity in the adult mouse utricles.
引用
收藏
页码:1 / 3
页数:3
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