Exploitation of gene context

被引:62
作者
Huynen, M
Snel, B
Lathe, W
Bork, P
机构
[1] European Mol Biol Lab, D-69117 Heidelberg, Germany
[2] Max Delbruck Ctr Mol Med, D-13122 Berlin, Germany
关键词
D O I
10.1016/S0959-440X(00)00098-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Recently, a number of techniques have been proposed that use completely sequenced genomes for the function prediction of individual proteins encoded therein. They use the fusion of genes, their conserved location in operons or merely their cooccurrence in genomes to predict the existence of functional interactions between the proteins they encode. This type of information complements functional features that are predicted by classical homology-based search techniques.
引用
收藏
页码:366 / 370
页数:5
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