Surgical risk reduction: Prophylactic salpingo-oophorectomy and prophylactic mastectomy

被引：51

作者：

Dowdy, SC

Stefanek, M

Hartmann, LC

机构：

[1] Mayo Clin & Mayo Fdn, Dept Obstet & Gynecol, Div Gynecol Surg, Rochester, MN 55905 USA

[2] NCI, Div Canc Control & Populat Sci, Behav Res Program, Bethesda, MD 20892 USA

[3] Mayo Clin Canc Ctr, Div Med Oncol, Dept Oncol, Rochester, MN USA

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 2004年 / 191卷 / 04期

关键词：

prophylactic; mastectomy; oophorectomy; breast cancer; ovarian cancer;

D O I：

10.1016/j.ajog.2004.04.028

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Investigators have used retrospective and prospective study designs to provide much needed data on the extent of risk reduction after prophylactic oophorectomy and mastectomy in women at increased risk for breast and ovarian cancer. In this publication we identify those women who may wish to consider prophylactic surgery, review data demonstrating the efficacy of prophylactic surgery, and discuss potential surgical complications. We also present data about the frequency of use and psychosocial impact of prophylactic surgery in this typically young group of women. Finally, we provide general treatment guidelines for the practicing clinician. (C) 2004 Elsevier Inc. All rights reserved.

引用

页码：1113 / 1123

页数：11

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