Synthesis of Terminal Vinylphosphonates Via Dbu-Promoted Tandem Phospha-Michael/Elimination Reactions

被引：14

作者：

Chen, Hui-Xuan ^{[1
]}

Huang, Lin-Jie ^{[1
]}

Liu, Jin-Biao ^{[1
]}

Weng, Jiang ^{[1
]}

Lu, Gui ^{[1
,2
]}

机构：

[1] Sun Yat Sen Univ, Sch Pharmaceut Sci, Inst Drug Synth & Pharmaceut Proc, Guangzhou 510006, Guangdong, Peoples R China

[2] Sun Yat Sen Univ, Inst Human Virol, Guangzhou 510080, Guangdong, Peoples R China

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2014年 / 189卷 / 12期

关键词：

Vinylphosphonates; beta-elimination; Michael addition; CHIRAL ALPHA-ARYL; ORGANIC-SYNTHESIS; SUBSTITUTED ETHYLPHOSPHONATES; ENANTIOSELECTIVE SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; VINYL PHOSPHONATES; DIPHENYL PHOSPHITE; MICHAEL ADDITION; PALLADIUM; ALDEHYDES;

D O I：

10.1080/10426507.2014.906422

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The terminal vinylphosphonates were prepared from various beta-nitroolefins and phosphites through tandem phospha-Michael/elimination reactions. In the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU), a variety of new vinylphosphonates were obtained in moderate to high yields under simple and mild condition. These new compounds were characterized by HRMS, H-1, C-13, and P-31 NMR techniques.

引用

页码：1858 / 1866

页数：9

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