Post-traumatic hypopituitarism and fatigue

被引：6
作者：
Masel, Brent E. [1 ]
Zgaljardic, Dennis J. [1 ]
Forman, Jack [1 ]
机构：
[1] Transit Learning Ctr, 1528 Post Off St, Galveston, TX 77550 USA
来源：
NEUROPSYCHOLOGICAL REHABILITATION | 2017年 / 27卷 / 07期
关键词：
Fatigue; Pituitary; Hormones; TRAUMATIC BRAIN-INJURY; QUALITY-OF-LIFE; GROWTH-HORMONE DEFICIENCY; RECOMBINANT HUMAN GH; ADULT PATIENTS; HYPOTHYROIDISM; REPLACEMENT; DISORDERS; SEVERITY; MODERATE;
D O I：
10.1080/09602011.2015.1125374
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Post-traumatic hypopituitarism (PTH) associated with chronic cognitive, psychiatric, and/or behavioural sequelae is common following moderate to severe traumatic brain injury (TBI). More specifically, due to a cascade of hormonal deficiencies secondary to PTH, individuals with TBI may experience debilitating fatigue that can negatively impact functional recovery, as it can limit participation in brain injury rehabilitation services and lead to an increase in maladaptive lifestyle practices. While the mechanisms underlying fatigue and TBI are not entirely understood, the current review will address the specific anatomy and physiology of the pituitary gland, as well as the association between pituitary dysfunction and fatigue in individuals with TBI.
引用
收藏
页码：1071 / 1079
页数：9
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