Paper-Based DNA Detection Using Lanthanide-Doped LiYF4 Upconversion Nanocrystals As Bioprobe

被引:42
作者
Ju, Qiang [1 ]
Uddayasankar, Uvaraj [1 ]
Krull, Ulrich [1 ]
机构
[1] Univ Toronto, Dept Chem & Phys Sci, Chem Sensors Grp, Mississauga, ON L5L 1C6, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
IMMOBILIZED QUANTUM DOTS; GOLD NANOPARTICLES; BIOSENSOR; PHASE; STRATEGY; DESIGN; DEVICE; SENSOR;
D O I
10.1002/smll.201400683
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A novel sensitive DNA bioassay using lanthanide-doped LiYF4 upconversion nanocrystals as luminescent marker and oligonucleotide hybridization as the selective reaction is developed in a paper-based platform, providing a detection limit of 3.6 fmol. (Figure Presented). © 2014 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:3912 / 3917
页数:6
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