Identification and genetic diversity of two human parvovirus B19 genotype 3 subtypes

被引：59
作者：
Parsyan, Armen
Szmaragd, Camille
Allain, Jean-Pierre
Candotti, Daniel [1 ]
机构：
[1] Univ Cambridge, Dept Haematol, Div Transfus Med, Cambridge, England
[2] Univ Cambridge, Dept Genet, Cambridge CB2 3EH, England
[3] Natl Blood Serv, Cambridge Blood Ctr, Cambridge, England
来源：
JOURNAL OF GENERAL VIROLOGY | 2007年 / 88卷
关键词：
D O I：
10.1099/vir.0.82496-0
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Three genotypes (1-3) of human parvovirus B19 have been identified. Analysis of 13 nearly full-length genotype 3 sequences from Ghana, Europe and Brazil identified two genetically distinct clusters. The classification of genotype 3 strains into two subtypes (B19/3a and B19/3b) is proposed. The rate of evolutionary change of B19 genotype 3 strains (2 x 10(-4) nucleotide substitutions per site per year) was similar to those of B19 genotype 1 and carnivore parvoviruses, supporting the hypothesis that high mutation rates are characteristic of members of the family Parvoviridae. The estimated divergence time between B19/3a and B19/3b is 525 years. In Ghana, subtype B19/3a is predominant.
引用
收藏
页码：428 / 431
页数：4
相关论文
共 19 条
  • [1] Characterization of parvovirus B19 genotype 2 in KU812Ep6 cells
    Blümel, J
    Eis-Hübinger, AM
    Stühler, A
    Bönsch, C
    Gessner, M
    Löwer, J
    [J]. JOURNAL OF VIROLOGY, 2005, 79 (22) : 14197 - 14206
  • [2] Identification and characterization of persistent human erythrovirus infection in blood donor samples
    Candotti, D
    Etiz, N
    Parsyan, A
    Allain, JP
    [J]. JOURNAL OF VIROLOGY, 2004, 78 (22) : 12169 - 12178
  • [3] Maternal-fetal transmission of human parvovirus B19 genotype 3
    Candotti, Daniel
    Danso, Kwabena
    Parsyan, Armen
    Dompreh, Albert
    Allain, Jean-Pierre
    [J]. JOURNAL OF INFECTIOUS DISEASES, 2006, 194 (05) : 608 - 611
  • [4] Genetic variants of parvovirus B19 identified in the United Kingdom: Implications for diagnostic testing
    Cohen, B. J.
    Gandhi, J.
    Clewley, J. P.
    [J]. JOURNAL OF CLINICAL VIROLOGY, 2006, 36 (02) : 152 - 155
  • [5] B19 virus genome diversity: epidemiological and clinical correlations
    Gallinella, G
    Venturoli, S
    Manaresi, E
    Musiani, M
    Zerbini, M
    [J]. JOURNAL OF CLINICAL VIROLOGY, 2003, 28 (01) : 1 - 13
  • [6] Prevalence of parvovirus B19 and parvovirus V9 DNA and antibodies in paired bone marrow and serum samples from healthy individuals
    Heegaard, ED
    Petersen, BL
    Heilmann, CJ
    Hornsleth, A
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (03) : 933 - 936
  • [7] Human parvovirus B19
    Heegaard, ED
    Brown, KE
    [J]. CLINICAL MICROBIOLOGY REVIEWS, 2002, 15 (03) : 485 - +
  • [8] Pathogenesis of parvovirus B19 infection: Host gene variability, and possible means and effects of virus persistence
    Kerr, JR
    [J]. JOURNAL OF VETERINARY MEDICINE SERIES B-INFECTIOUS DISEASES AND VETERINARY PUBLIC HEALTH, 2005, 52 (7-8): : 335 - 339
  • [9] Persistent B19 infection in immunocompetent individuals:: implications for transfusion safety
    Lefrère, JJ
    Servant-Delmas, A
    Candotti, D
    Mariotti, M
    Thomas, I
    Brossard, Y
    Lefère, F
    Girot, R
    Allain, JP
    Laperche, S
    [J]. BLOOD, 2005, 106 (08) : 2890 - 2895
  • [10] Evolutionary relationships among parvoviruses: Virus-host coevolution among autonomous primate parvoviruses and links between adeno-associated and avian parvoviruses
    Lukashov, VV
    Goudsmit, J
    [J]. JOURNAL OF VIROLOGY, 2001, 75 (06) : 2729 - 2740
12