One-Pot Silver-Catalyzed and PIDA-Mediated Sequential Reactions: Synthesis of Polysubstituted Pyrroles Directly from Alkynoates and Amines

被引：178

作者：

Liu, Weibing ^{[1
]}

Jiang, Huanfeng ^{[1
]}

Huang, Liangbin ^{[1
]}

机构：

[1] S China Univ Technol, Sch Chem & Chem Engn, Guangzhou 510640, Peoples R China

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 02期

关键词：

H BOND FUNCTIONALIZATION; EFFICIENT SYNTHESIS; REGIOSELECTIVE SYNTHESIS; CANNABIMIMETIC INDOLES; BIOLOGICAL EVALUATION; CYCLIZATION REACTIONS; SUBSTITUTED PYRROLES; ALKYNE AMIDATION; LAMELLARIN-O; DERIVATIVES;

D O I：

10.1021/ol9026478

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The addition/oxidative cyclization of alkynes with amines in the presence of AgBF4 catalyst and PIDA oxidant leads to polysubstituted pyrroles. The reaction corresponds to the construction of a pyrrole fragment, which also provides a new way to the formation of C-C bonds.

引用

页码：312 / 315

页数：4

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