A preoperative mathematic model for computed tomographic guided microwave ablation treatment of hepatic dome tumors

被引:4
作者
Gao, Fei [1 ,2 ,3 ]
Wang, Guo-Bao [2 ,3 ,4 ]
Xiang, Zhan-Wang [1 ,2 ,3 ]
Yang, Bin [5 ]
Xue, Jing-Bing [6 ]
Mo, Zhi-Qiang [1 ,2 ,3 ]
Zhong, Zhi-Hui [1 ,2 ,3 ]
Zhang, Tao [1 ,2 ,3 ]
Zhang, Fu-Jun [1 ,2 ,3 ]
Fan, Wei-Jun [1 ,2 ,3 ]
机构
[1] Sun Yat Sen Univ, Ctr Canc, Dept Intervent Radiol, Guangzhou 510060, Guangdong, Peoples R China
[2] State Key Lab Oncol South China, Guangzhou 510060, Guangdong, Peoples R China
[3] Collaborat Innovat Ctr Canc Med, Guangzhou 510060, Guangdong, Peoples R China
[4] Sun Yat Sen Univ, Ctr Canc, Dept Endoscopy, Guangzhou 510060, Guangdong, Peoples R China
[5] Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Gastrointestinal Surg, Guangzhou 510120, Guangdong, Peoples R China
[6] Univ Rochester, Med Ctr, Imaging Sci, Rochester, NY 14642 USA
基金
中国国家自然科学基金;
关键词
CT-guided; microwave ablation; hepatic dome; tumors; mathematic model; PERCUTANEOUS RADIOFREQUENCY ABLATION; ARTIFICIAL PLEURAL EFFUSION; HEPATOCELLULAR-CARCINOMA; DIAPHRAGMATIC INJURY; THERAPEUTIC-EFFICACY; THERMAL ABLATION; TIME VARIABLES; PORCINE MODEL; LIVER-TUMORS; ASCITES;
D O I
10.18632/oncotarget.8299
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose: This study sought to prospectively evaluate the feasibility and safety of a preoperative mathematic model for computed tomographic(CT) guided microwave(MW) ablation treatment of hepatic dome tumors. Methods: This mathematic model was a regular cylinder quantifying appropriate puncture routes from the bottom up. A total of 103 patients with hepatic dome tumors were enrolled and randomly divided into 2 groups based on whether this model was used or not: Group A (using the model; n = 43) versus Group B (not using the model; n = 60). All tumors were treated by CT-guided MW ablation and follow-up contrast CT were reviewed. Results: The average number of times for successful puncture, average ablation time, and incidence of right shoulder pain were less in Group A than Group B (1.4 vs. 2.5, P = 0.001; 8.8 vs. 11.1 minutes, P = 0.003; and 4.7% vs. 20%, P = 0.039). The technical success rate was higher in Group A than Group B (97.7% vs. 85.0%, P = 0.032). There were no significant differences between the two groups in primary and secondary technique efficacy rates (97.7% vs. 88.3%, P = 0.081; 90.0% vs. 72.7%, P = 0.314). No major complications occurred in both groups. Conclusion: The mathematic model of regular cylinder is feasible and safe for CT-guided MW ablation in treating hepatic dome tumors.
引用
收藏
页码:25949 / 25959
页数:11
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