Controversies in rheumatology: maintenance therapy with low-dose glucocorticoids in rheumatoid arthritis

被引：4

作者：

Buttgereit, Frank ^{[1
]}

Kvien, Tore K. ^{[2
]}

机构：

[1] Charite, Dept Rheumatol & Clin Immunol, Charitepl 1, D-10117 Berlin, Germany

[2] Diakonhjemmet Hosp, Div Rheumatol & Res, Oslo, Norway

来源：

RHEUMATOLOGY | 2022年 / 62卷 / 01期

关键词：

RA; prednisone; low-dose glucocorticoids; benefit-risk ratio; REMISSION; STRATEGY;

D O I：

10.1093/rheumatology/keac355

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Since the beginning of the use of glucocorticoids in clinical medicine, the risk-benefit ratio of these still very important drugs has been debated. There is no doubt that they produce many desirable therapeutic effects quickly and reliably. However, their potential to cause adverse effects, especially with prolonged use in high doses, limits their applicability. We discuss the arguments against and in favour of maintenance therapy with low-dose glucocorticoids in patients with RA, and present recent studies, assessments and conclusions on this question.

引用

页码：35 / 41

页数：7

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