Palladium(II) Complexes Containing Mixed Nitrogen- Sulphur Donor Ligands: Interaction of [Pd(Methionine Methyl Ester)(H2O) 2] 2+ with Biorelevant Ligands

被引：2

作者：

Shoukry, Mohamed M. ^{[1
,2
]}

Ezzat, Sameya M. T. ^{[2
]}

机构：

[1] Islamic Azad Univ, Fac Sci, Dept Chem, Madinah, Saudi Arabia

[2] Cairo Univ, Fac Sci, Dept Chem, Giza, Egypt

来源：

BIOINORGANIC CHEMISTRY AND APPLICATIONS | 2014年 / 2014卷

关键词：

BIS(PLATINUM) COMPLEXES; DIAQUA(ETHYLENEDIAMINE)PALLADIUM(II) COMPLEXES; MONOPHOSPHATE; EQUILIBRIUM; CHEMISTRY;

D O I：

10.1155/2014/382646

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Pd(MME)Cl-2 complex (MME = methionine methyl ester) was synthesised and characterized by physicochemical measurements. The reaction of [Pd(MME)(H2O)(2)](2+) with amino acids, peptides, or dicarboxylic acids was investigated at 25 degrees C and 0.1 M ionic strength. Amino acids and dicarboxylic acids form 1 : 1 complexes. Peptides form both 1 : 1 complexes and the corresponding deprotonated amide species. The stability of the complexes formed was determined and the binding centres of the ligands were assigned. Effect of solvent on the stability constant of Pd(MME)- CBDCA complex, taken as a representative example, shows that the complex is more favoured in a medium of low dielectric constant. The concentration distribution diagrams of the complexes were evaluated.

引用

页数：8

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