Atypical progressive multifocal leukoencephalopathy (PML) in a patient with pulmonary sarcoidosis

被引：3
作者：
Le Guilloux, J. [1 ]
Roubiou, C. [4 ]
Mallet, J. [1 ]
Bouvry, D. [3 ]
Alkhalil, A. [1 ]
Coman, I. [1 ]
Belin, C. [1 ]
Gorochov, G. [5 ]
Carpentier, A. [2 ]
Mokhtari, K. [2 ]
Carpentier, A. -F. [1 ]
机构：
[1] CHU Avicenne, Serv Neurol, F-93009 Bobigny, France
[2] CHU Pitie Salpetriere, Serv Neurochirurg, F-75013 Paris, France
[3] CHU Avicenne, Serv Pneumol, F-93009 Bobigny, France
[4] CHR Belfort Montbeliard, Serv Med Interne & Geriatrie, F-90016 Belfort, France
[5] CHU Pitie Salpetriere, Lab Immunol Cellulaire & Tissulaire, F-75013 Paris, France
来源：
REVUE NEUROLOGIQUE | 2010年 / 166卷 / 03期
关键词：
Progressive multifocal leukoencephalopathy; Sarcoidosis; Contrast enhancement; Immunodepression; JC virus; HUMAN IMMUNODEFICIENCY VIRUS; CEREBROSPINAL-FLUID; INFECTED PATIENTS; NERVOUS-SYSTEM; MR-IMAGES; AIDS; ASSOCIATION; DIAGNOSIS; SURVIVAL; NEUROSARCOIDOSIS;
D O I：
10.1016/j.neurol.2009.05.015
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Introduction. - Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of central nervous system due to the JC virus. PML generally occurs in immunocompromised hosts and has a fatal outcome. Observation. - We report a case of an atypical PML in a patient with pulmonary sarcoidosis: MRI showed multifocal and punctate contrast enhancements. The diagnostic was made by brain biopsy. Conclusion. - The pathophysiology of this association is probably related to the immunodepression induced by sarcoidosis. (C) 2009 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：341 / 345
页数：5
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