Determination of phenazopyridine in human plasma by high performance liquid chromatography

被引：18

作者：

Farin, D ^{[1
]}

Piva, G ^{[1
]}

Kitzes-Cohen, R ^{[1
]}

机构：

[1] Technion Israel Inst Technol, Bruce Rappaport Fac Med, Carmel Med Ctr, Clin Pharmacol & Infect Dis Unit, IL-31096 Haifa, Israel

来源：

CHROMATOGRAPHIA | 2000年 / 52卷 / 3-4期

关键词：

column liquid chromatography; phenazopyridine; human plasma;

D O I：

10.1007/BF02490452

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A simple, low-cost, sensitive and selective HPLC method was developed for the determination of phenazopyridine in human plasma. The method employs UV detection of phenazopyridine and of the Internal Standard at 2 different wavelengths. Calibration curves were linear over a large dynamic range, i.e., within 0.05-10.0 mu g mL(-1) with limit of quantification of 0.05 mu g mL(-1),and a limit of detection of 0.01 mu g mL(-1).

引用

页码：179 / 180

页数：2

共 4 条

[1] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF PHENAZOPYRIDINE HYDROCHLORIDE, TETRACYCLINE HYDROCHLORIDE AND SULFAMETHIZOLE IN COMBINATION [J].