Mechanisms of angiogenesis and arteriogenesis

被引：3258
|
作者：
Carmeliet, P [1 ]
机构：
[1] Katholieke Univ Leuven VIB, Ctr Transgene Technol & Gene Therapy, B-3000 Louvain, Belgium
来源：
NATURE MEDICINE | 2000年 / 6卷 / 04期
关键词：
D O I：
10.1038/74651
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Endothelial and smooth muscle cells interact wit each other to form new blood vessels. In this review, the cellular and molecular mechanisms underlying the formation of endothelium-lined channels (angiogenesis) and their maturation via recruitment of smooth muscle cells (arteriogenesis) during physiological and pathological conditions are summarized, alongside with possible therapeutic applications.
引用
收藏
页码：389 / 395
页数：7
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