Mechanisms of angiogenesis and arteriogenesis

被引：3297

作者：

Carmeliet, P ^{[1
]}

机构：

[1] Katholieke Univ Leuven VIB, Ctr Transgene Technol & Gene Therapy, B-3000 Louvain, Belgium

来源：

NATURE MEDICINE | 2000年 / 6卷 / 04期

关键词：

D O I：

10.1038/74651

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Endothelial and smooth muscle cells interact wit each other to form new blood vessels. In this review, the cellular and molecular mechanisms underlying the formation of endothelium-lined channels (angiogenesis) and their maturation via recruitment of smooth muscle cells (arteriogenesis) during physiological and pathological conditions are summarized, alongside with possible therapeutic applications.

引用

页码：389 / 395

页数：7

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