Mach-Zehnder interferometer based integrated-photonic acetone sensor approaching the sub-ppm level detection limit

The detection of acetone in the gaseous form in exhaled breath using an integrated sensor can provide an effective tool for disease diagnostics as acetone is a marker tbr monitoring human metabolism. An on-chip acetone gas sensor based on the principle of Mach-Zehnder interferometer is proposed and demonstrated. The sensing arm of the device is activated with a composite film of polyethyleneimine and amido-graphene oxide as the gas-sensitive adsorption layer. The composite film demonstrates good selectivity to acetone gas, can be used repeatedly, and is stable in long-term use. Room temperature operation has been demonstrated for the sensor with high sensitivity under a 20 ppm acetone environment. The detection limit can reach 0.76 ppm, making it feasible to be used for the clinical diagnosis of diabetes and the prognosis of heart failure. (C) 2022 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement