What structural modifications can be used for BRD4 inhibitors for their use in leukemia therapy?

被引：0
|
作者：
Yao, Dahong [1 ,2 ]
Liu, Jie [1 ,2 ]
Ouyang, Liang [1 ,2 ]
机构：
[1] Sichuan Univ, West China Hosp, Ctr Canc, Lab Drug Discovery, Chengdu 610041, Peoples R China
[2] Collaborat Innovat Ctr Biotherapy, Chengdu 610041, Peoples R China
来源：
FUTURE MEDICINAL CHEMISTRY | 2017年 / 9卷 / 09期
基金：
中国国家自然科学基金;
关键词：
BRD4; inhibitors; leukemia; modification strategies; BET BROMODOMAIN INHIBITOR; ACUTE MYELOID-LEUKEMIA; TERMINAL DOMAIN; DISCOVERY; POTENT; KINASE; FAMILY; MYC;
D O I：
10.4155/fmc-2017-0084
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：839 / 842
页数：4
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