Production of Tetrahydrocurcumin From Curcumin by Cultured Plant Cells and Inhibitory Effects of Curcuminoids on NF-κB Activity

被引：1

作者：

Shimoda, Kei ^{[1
]}

Kubota, Naoji ^{[1
]}

Fujitaka, Yuya ^{[2
]}

Hamada, Hiroki ^{[2
]}

Inoue, Manami ^{[2
]}

Hamada, Hatsuyuki ^{[3
]}

Yanagi, Masayoshi ^{[2
]}

Onishi, Tatsuya ^{[2
]}

机构：

[1] Oita Univ, Fac Med, Dept Biomed Chem, Oita, Japan

[2] Okayama Univ Sci, Fac Sci, Dept Life Sci, Okayama, Japan

[3] Natl Inst Fitness & Sports Kanoya, Kagoshima, Japan

来源：

NATURAL PRODUCT COMMUNICATIONS | 2019年 / 14卷 / 09期

关键词：

biotransformation; reduction; Morus sp; curcumin; tetrahydrocurcumin; NF-kappa B; GLYCOSYLATION; COLITIS;

D O I：

10.1177/1934578X19878920

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Biotransformation of curcumin was investigated using cultured plant cells of Morus sp. Cultured Morus cells converted curcumin into dihydrocurcumin and tetrahydrocurcumin. The activity of nuclear factor-kappa B was inhibited by curcumin and tetrahydrocurcumin.

引用

页数：3

共 10 条

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