Infliximab therapy induces increased polyclonality of CD4+CD25+regulatory T cells in psoriasis

被引：15
作者：
Diluvio, L. [1 ]
Romiti, M. L. [2 ]
Angelini, F. [2 ,3 ]
Campione, E. [1 ]
Rossi, P. [2 ,3 ]
Prinz, J. C. [4 ]
Chimenti, S. [1 ]
Lamioni, A. [5 ]
机构：
[1] Univ Roma Tor Vergata, Dept Dermatol, I-00133 Rome, Italy
[2] Univ Roma Tor Vergata, Dept Pediat, I-00133 Rome, Italy
[3] Childrens Hosp Bambino Gesu, Div Infect Dis & Immunol, Rome, Italy
[4] Univ Munich, Dept Dermatol, D-8000 Munich, Germany
[5] ANMI ONLUS, Rome, Italy
来源：
BRITISH JOURNAL OF DERMATOLOGY | 2010年 / 162卷 / 04期
关键词：
infliximab; psoriasis; regulatory T cells; spectratyping; T-cell receptor; REPERTOIRE DIVERSITY; ALPHA; RECONSTITUTION; DISEASE; BLOOD;
D O I：
10.1111/j.1365-2133.2010.09650.x
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
引用
收藏
页码：895 / 897
页数：3
相关论文
共 10 条
  • [1] Serum levels of TNF-α, IFN-γ, IL-6, IL-8, IL-12, IL-17 and IL-18 in patients with active psoriasis and correlation with disease severity
    Arican, O
    Aral, M
    Sasmaz, S
    Ciragil, P
    [J]. MEDIATORS OF INFLAMMATION, 2005, (05) : 273 - 279
  • [2] T-CELL ANTIGEN RECEPTOR GENES AND T-CELL RECOGNITION
    DAVIS, MM
    BJORKMAN, PJ
    [J]. NATURE, 1988, 334 (6181) : 395 - 402
  • [3] Psoriasis assessment tools in clinical trials
    Feldman, SR
    Krueger, GG
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 2005, 64 : 65 - 68
  • [4] Rapid T-cell receptor CD4+ repertoire reconstitution and immune recovery in unrelated umbilical cord blood transplanted pediatric leukemia patients
    Finocchi, Andrea
    Romiti, Maria Luisa
    Di Cesare, Silvia
    Puliafito, Pamela
    Pensieroso, Simone
    Rana, Ippolita
    Pinto, Rita
    Cancrini, Caterina
    De Rossi, Giulio
    Caniglia, Maurizio
    Rossi, Paolo
    [J]. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2006, 28 (07) : 403 - 411
  • [5] TCRαβ repertoire diversity of human naturally occurring CD4+CD25+ regulatory T cells
    Fujishima, M
    Hirokawa, M
    Fujishima, N
    Sawada, K
    [J]. IMMUNOLOGY LETTERS, 2005, 99 (02) : 193 - 197
  • [6] Human CD4+CD25+ regulatory T cells share equally complex and comparable repertoires with CD4+CD25-counterparts
    Kasow, KA
    Chen, XH
    Knowles, J
    Wichlan, D
    Handgretinger, R
    Riberdy, JM
    [J]. JOURNAL OF IMMUNOLOGY, 2004, 172 (10) : 6123 - 6128
  • [7] The role of T cells in psoriasis
    Prinz, JC
    [J]. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2003, 17 (03) : 257 - 270
  • [8] Anti tumour necrosis-α therapy increases the number of FOXP3+ regulatory T cells in children affected by Crohn's disease
    Ricciardelli, Ida
    Lindley, Keith J.
    Londei, Marco
    Quaratino, Sonia
    [J]. IMMUNOLOGY, 2008, 125 (02) : 178 - 183
  • [9] Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis:: Mechanism underlying unrestrained pathogenic effector T cell proliferation
    Sugiyama, H
    Gyulai, R
    Toichi, E
    Garaczi, E
    Shimada, S
    Stevens, SR
    McCormick, TS
    Cooper, KD
    [J]. JOURNAL OF IMMUNOLOGY, 2005, 174 (01) : 164 - 173
  • [10] Wu CJ, 2000, BLOOD, V95, P352
1