MERTK is a potential therapeutic target in osimertinib-resistant non-small cell lung cancer

被引:1
|
作者
Yan, Dan [1 ]
Huelse, Justus [1 ]
Parker, Rebecca [1 ]
Wang, Xiaodong [2 ]
Frye, Stephen V. [2 ]
Earp, H. Shelton [3 ]
DeRyckere, Deborah [1 ]
Graham, Douglas [1 ]
机构
[1] Childrens Healthcare Atlanta, Aflac Canc & Blood Disorders Ctr, Atlanta, GA USA
[2] Ctr Integrat Chem Biol & Drug Discovery, Chapel Hill, NC USA
[3] Sch Med, Chapel Hill, NC USA
关键词
D O I
10.1158/1538-7445.SABCS18-4765
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
4765
引用
收藏
页数:2
相关论文
共 50 条
  • [21] Placenta-specific 8 is a potential novel target for osimertinib resistance in non-small cell lung cancer
    Fei, Xiaoyun
    Wang, Gang
    Shen, Hui
    Gu, Xiaohua
    ONCOLOGY LETTERS, 2019, 18 (01) : 955 - 961
  • [22] Case report: Durable response of ensartinib targeting EML4-ALK fusion in osimertinib-resistant non-small cell lung cancer
    Guo, Yongkuan
    Zhang, Ran
    Meng, Yiran
    Wang, Li
    Zheng, Liuqing
    You, Jian
    FRONTIERS IN PHARMACOLOGY, 2024, 15
  • [23] The therapeutic efficacy of osimertinib in non-small cell lung cancer with malignant pleural effusion
    Nagamine, Hiroaki
    Sawa, Kenji
    Kaneda, Hiroyasu
    Ogawa, Koichi
    Nakahama, Kenji
    Matsumoto, Yoshiya
    Tani, Yoko
    Mitsuoka, Shigeki
    Kimura, Tatsuo
    Kawaguchi, Tomoya
    ANNALS OF ONCOLOGY, 2022, 33 : S523 - S523
  • [24] Olaparib Combined With Dacomitinib in Osimertinib-Resistant Brain and Leptomeningeal Metastases From Non-Small Cell Lung Cancer: A Case Report and Systematic Review
    Zhang, Hui
    Wang, Yong
    Wu, Huaguo
    Zhou, Shizhen
    Li, Shuo
    Meng, Xiangji
    Tao, Rongjie
    Yu, Jinming
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [25] ING2-WTAP is a potential therapeutic target in non-small cell lung cancer
    Cheng, Hao
    Wang, Shi-Jiang
    Li, Zhi
    Ma, Yan
    Song, Yang-Rong
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2022, 605 : 31 - 38
  • [26] Unlocking the potential of CD70 as a therapeutic target in non-small cell lung cancer
    Jacobs, Julie
    Pauwels, Patrick
    Rolfo, Christian
    Lardon, Filip
    Deschoolmeester, Vanessa
    Deben, Christophe
    Van den Bossche, Jolien
    Zwaenepoel, Karen
    Hermans, Christophe
    Silence, Karen
    Thibault, Alain
    CANCER RESEARCH, 2015, 75
  • [27] Midkine Is a Potential Therapeutic Target of Tumorigenesis, Angiogenesis, and Metastasis in Non-Small Cell Lung Cancer
    Shin, Dong Hoon
    Jo, Jeong Yeon
    Kim, Sun Ha
    Choi, Minyoung
    Han, Chungyong
    Choi, Beom K.
    Kim, Sang Soo
    CANCERS, 2020, 12 (09) : 1 - 20
  • [28] Tumor Vasculature as a Therapeutic Target in Non-small Cell Lung Cancer
    Bar, Jair
    Goss, Glenwood D.
    JOURNAL OF THORACIC ONCOLOGY, 2012, 7 (03) : 609 - 620
  • [29] MERTK Inhibition: Potential as a Treatment Strategy in EGFR Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer
    Chen, Chao-Ju
    Liu, Yu-Peng
    PHARMACEUTICALS, 2021, 14 (02) : 1 - 25
  • [30] BBT-176, a Novel Fourth-Generation Tyrosine Kinase Inhibitor for Osimertinib-Resistant EGFR Mutations in Non-Small Cell Lung Cancer
    Lim, Sun Min
    Fujino, Toshio
    Lee, Gwanghee
    Kim, Chulwon
    Lee, Yong-Hee
    Kim, Dong-Wan
    Ahn, Jin Seok
    Mitsudomi, Tetsuya
    Jin, Taiguang
    Lee, Sang-Yoon
    CLINICAL CANCER RESEARCH, 2023, 29 (16) : 3004 - 3016