A porphyrin-basesd fluorescent probe for optical detection of toxic Cd2+ ion in aqueous solution and living cells

被引：54
作者：
Huang, Wen-Bin [1 ,2 ]
Gu, Wei [1 ,2 ]
Huang, Hong-Xia [1 ]
Wang, Jun-Bo [1 ]
Shen, Wang-Xing [1 ]
Lv, Yuan-Yuan [1 ]
Shen, Jie [1 ]
机构：
[1] Zhejiang Univ City Coll, Sch Med, Hangzhou 310015, Zhejiang, Peoples R China
[2] Zhejiang Univ, Coll Chem & Biol Engn, Hangzhou 310027, Zhejiang, Peoples R China
来源：
DYES AND PIGMENTS | 2017年 / 143卷
基金：
美国国家科学基金会;
关键词：
Cadmium ion; Porphyrin; Fluorescent chemosensor; Ratiometric sensor; Intramolecular charge transfer (ICT); Cell imaging; PHYSIOLOGICAL PH; CADMIUM IONS; ZINC IONS; EMISSION-SPECTROMETRY; SENSOR; CHEMOSENSOR; ZN2+; WATER; SHIFT; HG2+;
D O I：
10.1016/j.dyepig.2017.05.001
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A porphyrin-based water-soluble fluorescent probe was reported for ratiometric detection of cadmium ion (Cd2+) in aqueous solution. This probe bearing two 2,2'-dipyridylamine (DPA) groups as metal chelating moieties which show chelation-produced ratiometric fluorescence effect with Cd2+ via the interruption of intramolecular charge transfer (ICT) process. Exhibiting a large ratiometric fluorescence signal, the probe shows high sensitivity, high selectivity as well as quick response when detecting Cd2+ in the physiological pH window with a detection limit of part per billion (ppb) level. Moreover, it displays very low cytotoxicity and can be employed to visualize intracellular Cd2+ in living cells by utilizing laser scanning confocal microscopy. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码：427 / 435
页数：9
相关论文
共 61 条
[1]   A highly sensitive and selective ratiometric Cd2+ fluorescent sensor for distinguishing Cd2+ from Zn2+ based on both fluorescence intensity and emission shift [J].
Bao, Yinyin ;
Liu, Bin ;
Wang, Hu ;
Du, Fanfan ;
Bai, Ruke .
ANALYTICAL METHODS, 2011, 3 (06) :1274-1276
[2]   A porphyrin-based near-infrared fluorescent sensor for sulfur ion detection and its application in living cells [J].
Cheng, Fenmin ;
Wu, Xiangsi ;
Liu, Mali ;
Lon, Yunfei ;
Chen, Guanfan ;
Zeng, Rongjin .
SENSORS AND ACTUATORS B-CHEMICAL, 2016, 228 :673-678
[3]   Direct determination of cadmium in urine by tungsten-coil inductively coupled plasma atomic emission spectrometry using palladium as a permanent modifier [J].
Davis, Amanda C. ;
Calloway, Clifton P., Jr. ;
Jones, Bradley T. .
TALANTA, 2007, 71 (03) :1144-1149
[4]   Development of Ion Chemosensors Based on Porphyrin Analogues [J].
Ding, Yubin ;
Zhu, Wei-Hong ;
Xie, Yongshu .
CHEMICAL REVIEWS, 2017, 117 (04) :2203-2256
[5]   Fibroblasts From Long-Lived Rodent Species Exclude Cadmium [J].
Dostal, Lubomir ;
Kohler, William M. ;
Penner-Hahn, James E. ;
Miller, Richard A. ;
Fierke, Carol A. .
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2015, 70 (01) :10-19
[6]   Separation and determination of cadmium in water by foam column prior to inductively coupled plasma optical emission spectrometry [J].
El-Shahawi, M. S. ;
Bashammakh, A. S. ;
Orief, M. I. ;
Alsibaai, A. A. ;
Al-Harbi, E. A. .
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 2014, 20 (01) :308-314
[7]   A simple highly sensitive and selective TURN-ON fluorescent chemosensor for the detection of cadmium ions in physiological conditions [J].
Ellairaja, Sundaram ;
Manikandan, Ramar ;
Vijayan, Muthunan Thevar ;
Rajagopal, Seenivasan ;
Vasantha, Vairathevar Sivasamy .
RSC ADVANCES, 2015, 5 (78) :63287-63295
[8]   Self-association of 5,10,15,20-tetrakis-(4-sulfonatophenyl)-porphyrin tuned by poly(decylviologen) and sulfobutylether-β-cyclodextrin [J].
Flores, Mario E. ;
Sano, Naoki ;
Araya-Hermosilla, Rodrigo ;
Shibue, Toshimichi ;
Olea, Andres F. ;
Nishide, Hiroyuki ;
Moreno-Villoslada, Ignacio .
DYES AND PIGMENTS, 2015, 112 :262-273
[9]   Structures and photoinduced electron transfer of protonated complexes of porphyrins and metallophthalocyanines [J].
Fukuzumi, Shunichi ;
Honda, Tatsuhiko ;
Kojima, Takahiko .
COORDINATION CHEMISTRY REVIEWS, 2012, 256 (21-22) :2488-2502
[10]   Structural changes accompanying intramolecular electron transfer: Focus on twisted intramolecular charge-transfer states and structures [J].
Grabowski, ZR ;
Rotkiewicz, K ;
Rettig, W .
CHEMICAL REVIEWS, 2003, 103 (10) :3899-4031
1234567