Analyzing of Alzheimer's Disease Based on Biomedical and Socio-Economic Approach Using Molecular Communication, Artificial Neural Network, and Random Forest Models

被引:10
作者
Bayraktar, Yuksel [1 ]
Isik, Esme [2 ]
Isik, Ibrahim [3 ]
Ozyilmaz, Ayfer [4 ]
Toprak, Metin [5 ]
Kahraman Guloglu, Fatma [6 ]
Aydin, Serdar [7 ]
机构
[1] Istanbul Univ, Dept Econ, TR-34452 Istanbul, Turkey
[2] Malatya Turgut Ozal Univ, Dept Opt, TR-44700 Malatya, Turkey
[3] Inonu Univ, Dept Elect Elect Engn, TR-44280 Malatya, Turkey
[4] Kocaeli Univ, Dept Foreign Trade, TR-41650 Kocaeli, Turkey
[5] Istanbul Sabahattin Zaim Univ, Dept Econ, TR-34303 Istanbul, Turkey
[6] Yalova Univ, Dept Social Work, TR-77100 Yalova, Turkey
[7] Southern Illinois Univ Carbondale, Sch Hlth Sci, 1365 Douglas Dr, Carbondale, IL 62901 USA
关键词
Alzheimer's disease; molecular communication; amyloid beta; socioeconomic; random forest; neural network; Turkey; number of received molecules; total population; income inequality; AMYLOID-BETA; EDUCATION; DEMENTIA; DIFFUSION; DETERMINANTS; POPULATION; BIOLOGY; SYSTEMS; RISK;
D O I
10.3390/su14137901
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Alzheimer's disease will affect more people with increases in the elderly population, as the elderly population of countries everywhere generally rises significantly. However, other factors such as regional climates, environmental conditions and even eating and drinking habits may trigger Alzheimer's disease or affect the life quality of individuals already suffering from this disease. Today, the subject of biomedical engineering is being studied intensively by many researchers considering that it has the potential to produce solutions to various diseases such as Alzheimer's caused by problems in molecule or cell communication. In this study, firstly, a molecular communication model with the potential to be used in the treatment and/or diagnosis of Alzheimer's disease was proposed, and its results were analyzed with an artificial neural network model. Secondly, the ratio of people suffering from Alzheimer's disease to the total population, along with data of educational status, income inequality, poverty threshold, and the number of the poor in Turkey were subjected to detailed distribution analysis by using the random forest model statistically. As a result of the study, it was determined that a higher income level was causally associated with a lower risk of Alzheimer's disease.
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页数:15
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