Cytokine levels in malignant ascites and peripheral blood of patients with advanced ovarian cancer

被引：35
|
作者：
Radke, J
Schmidt, D
Bohme, M
Schmidt, U
Weise, W
Morenz, J
机构：
[1] OTTO VONGUERICKE UNIV,FAK MED,INST IMMUNOL,D-39008 MAGDEBURG,GERMANY
[2] OTTO VONGUERICKE UNIV,FAK MED,KLIN ST MARIENSTIFT MAGDEBURG,D-39008 MAGDEBURG,GERMANY
[3] OTTO VONGUERICKE UNIV,FAK MED,INST BIOMETRIE & MED INFORMAT,D-39008 MAGDEBURG,GERMANY
来源：
GEBURTSHILFE UND FRAUENHEILKUNDE | 1996年 / 56卷 / 02期
关键词：
D O I：
10.1055/s-2007-1022247
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
The concentrations of various cytokines were examined by ELISA in blood and in ascites from 14 patients with advanced ovarian cancer (stage IV). The control group consisted of 6 patients with benign gynaecological disorders. Compared with patients with benign gynaecological disorders, ascites and/or plasma of patients with ovarian cancer showed significantly higher levels of IL-6, IL-8, IL-10, TNF-alpha, and sIL-2R. There were no increases of IL-1 alpha, IL-1 beta, IL-2, IFN-gamma, and sCD14 levels. The possible pathogenetic significance of cytokines in ovarian cancer is discussed.
引用
收藏
页码：83 / 87
页数：5
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