General practitioners' perceptions of vaccination controversies: a French nationwide cross-sectional study

被引:20
作者
Le Marechal, M. [1 ]
Fressard, L. [2 ,3 ]
Agrinier, N. [1 ,4 ]
Verger, P. [2 ,3 ,5 ]
Pulcini, C. [1 ,2 ,6 ]
机构
[1] Univ Lorraine, EA APEMAC 4360, Nancy, France
[2] Aix Marseille Univ, INSERM, IRD, SESSTIM, Marseille, France
[3] ORS PACA, Marseille, France
[4] CHRU Nancy, INSERM, CIC Epidemiol Clin 1433, Nancy, France
[5] INSERM, F CRIN, I Reivac Innovat Clin Res Network Vaccinol, Paris, France
[6] CHRU Nancy, Serv Malad Infect & Trop, Nancy, France
关键词
Anti-vaccination movement; Anti-vaccine website; General practitioners; Surveys and questionnaires vaccination; INFLUENZA; KNOWLEDGE; HESITANCY; VACCINES; DESIGN;
D O I
10.1016/j.cmi.2017.10.021
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Objectives: We aimed to study general practitioners' (GPs') perceptions of vaccines that have been a subject of controversy in France. Methods: A cross-sectional survey in 2014 asked a representative national sample of GPs, randomly selected from the exhaustive database of health professionals in France, about their perceptions of the likelihood of serious adverse events potentially associated with six different vaccines: for two of them the association was based on some scientific evidence, whereas for the other four this is not the case. We performed a cluster analysis to construct a typology of GPs' perceptions about the likelihood of these potential six associations. Factors associated with certain clusters of interest were identified using logistic regression models. Results: Overall, 1582 GPs participated in the questionnaire survey (1582/1712 GPs who agreed to participate, 92%). Cluster analysis identified four groups of GPs according to their susceptibility to vaccine controversies: 1) limited susceptibility to controversies (52%); 2) overall unsure, but rejected the association between hepatitis B vaccine and multiple sclerosis (32%); 3) highly susceptible to controversies (11%); and 4) unsure (5%). We found that GPs who occasionally practised alternative medicine (OR 2.71, 95% CI 1.65-4.45), and those who considered information provided by mass media as reliable (OR 2.04, 95% CI 1.65-3.99) were more susceptible to controversies. Conclusions: GPs had different profiles of susceptibility to vaccination controversies, and most of their perceptions of these controversies were not based on scientific evidence. (C) 2017 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:858 / 864
页数:7
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