Antioxidant and antifungal activities of Camellia sinensis (L.) Kuntze leaves obtained by different forms of production

被引:27
作者
Camargo, L. E. A. [1 ]
Pedroso, L. S. [1 ]
Vendrame, S. C. [2 ]
Mainardes, R. M. [2 ]
Khalil, N. M. [2 ]
机构
[1] Fac Guairaca, Dept Pharm, Rua 15 Novembro 7050, BR-85010000 Guarapuava, PR, Brazil
[2] Univ Estadual Ctr Oeste UNICTR, Lab Pharmaceut Nanotechnol, Rua Simeao Camargo Varela de Sa 03, BR-85040080 Guarapuava, PR, Brazil
关键词
teas; fermentation method; Candida spp; phenolic compounds; reactive oxygen species; OXIDATIVE STRESS; BLACK TEA; GREEN TEA; MYELOPEROXIDASE; SUSCEPTIBILITY; POLYPHENOLS; INHIBITION; TOXICITY; EXTRACTS; SERUM;
D O I
10.1590/1519-6984.18814
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The antioxidant and anticandidal activities of leaves obtained from Camellia sinensis by non-fermentation (green and white teas), semi-fermentation (red tea) and fermentation method (black tea) were investigated. It was evaluated the total phenolic content by Folin-Ciocalteau assay; antioxidant capacities were evaluated in vitro using DPPH and ABTS radicals, hypochlorous acid and superoxide anion scavenger assays, induced hemolysis, lipid peroxidation by conjugated diene formation and myeloperoxidase activity. Anticandidal activity was performed on three strains of Candida spp. The results showed that non-fermented teas have a higher concentration of phenolic compounds, and then presented the best inhibitory activity of AAPH-induced hemolysis, the best inhibition of conjugated diene formation and more pronounced antioxidant activity in all tests. The highest anticandidal activity was obtained from fermented tea, followed by non-fermented tea. These results indicate that the antioxidant activity demonstrated has no direct relation with the anticandidal activity.
引用
收藏
页码:428 / 434
页数:7
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