Timing of Statistical Benefit of Mineralocorticoid Receptor Antagonists Among Patients With Heart Failure and Post-Myocardial Infarction

被引:13
作者
Bedrouni, Wassim [1 ]
Sharma, Abhinav [2 ]
Pitt, Bertram [3 ]
Lam, Carolyn S. P. [4 ,5 ]
Ni, Jiayi [2 ]
Ferreira, Joao Pedro [6 ,7 ,8 ]
McMurray, John [9 ]
Giannetti, Nadia [6 ,7 ]
Girerd, Nicolas [2 ]
Rossignol, Patrick [6 ,7 ]
Solomon, Scott D. [10 ]
Claggett, Brian [10 ]
Pocock, Stuart [11 ]
Huynh, Thao [2 ]
Zannad, Faiez [6 ,7 ]
机构
[1] McGill Univ, Hlth Ctr, Dept Med, Montreal, PQ, Canada
[2] McGill Univ, Hlth Ctr, Div Cardiol, Montreal, PQ, Canada
[3] Univ Michigan, Sch Med, Dept Med, Ann Arbor, MI USA
[4] Natl Heart Ctr Singapore, Dept Cardiol, Singapore, Singapore
[5] Duke Natl Univ Singapore, Singapore, Singapore
[6] Univ Lorraine, Invest Clin Plurithemat 1433, Nancy, France
[7] Univ Lorraine, Inserm U1116, CHRU Nancy, FCRIN INI CRCT Cardiovasc & Renal Clin Trialists, Nancy, France
[8] Univ Porto, Fac Med, Dept Surg & Physiol, Cardiovasc Res & Dev Ctr, Porto, Portugal
[9] Univ Glasgow, BHF Cardiovasc Res Ctr, Glasgow, Scotland
[10] Brigham & Womens Hosp, Div Cardiovasc Med, Boston, MA USA
[11] London Sch Hyg & Trop Med, Dept Med Stat, London, England
关键词
eplerenone; morbidity; myocardial infarction; prognosis; spironolactone; SPIRONOLACTONE; DYSFUNCTION; EPLERENONE; MORTALITY;
D O I
10.1161/CIRCHEARTFAILURE.121.009295
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:3
相关论文
共 5 条
  • [1] Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction
    Pitt, B
    Remme, W
    Zannad, F
    Neaton, J
    Martinez, F
    Roniker, B
    Bittman, R
    Hurley, S
    Kleiman, J
    Gatlin, M
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (14) : 1309 - 1321
  • [2] Eplerenone reduces mortality 30 days after randomization following acute myocardial infarction in patients with left ventricular systolic dysfunction and heart failure
    Pitt, B
    White, H
    Nicolau, J
    Martinez, F
    Gheorghiade, M
    Aschermann, M
    van Veldhuisen, DJ
    Zannad, F
    Krum, H
    Mukherjee, R
    Vincent, J
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 46 (03) : 425 - 431
  • [3] The effect of spironolactone on morbidity and mortality in patients with severe heart failure
    Pitt, B
    Zannad, F
    Remme, WJ
    Cody, R
    Castaigne, A
    Perez, A
    Palensky, J
    Wittes, J
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (10) : 709 - 717
  • [4] Spironolactone for Heart Failure with Preserved Ejection Fraction
    Pitt, Bertram
    Pfeffer, Marc A.
    Assmann, Susan F.
    Boineau, Robin
    Anand, Inder S.
    Claggett, Brian
    Clausell, Nadine
    Desai, Akshay S.
    Diaz, Rafael
    Fleg, Jerome L.
    Gordeev, Ivan
    Harty, Brian
    Heitner, John F.
    Kenwood, Christopher T.
    Lewis, Eldrin F.
    O'Meara, Eileen
    Probstfield, Jeffrey L.
    Shaburishvili, Tamaz
    Shah, Sanjiv J.
    Solomon, Scott D.
    Sweitzer, Nancy K.
    Yang, Song
    McKinlay, Sonja M.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (15) : 1383 - 1392
  • [5] Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms.
    Zannad, Faiez
    McMurray, John J. V.
    Krum, Henry
    van Veldhuisen, Dirk J.
    Swedberg, Karl
    Shi, Harry
    Vincent, John
    Pocock, Stuart J.
    Pitt, Bertram
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2011, 364 (01) : 11 - 21