Sudden infant death syndrome due to parainfluenza virus 2 associated with hemophagocytic syndrome

被引:5
作者
Kashiwagi, Y
Kawashima, H
Kanetaka, Y
Ioi, H
Takekuma, K
Hoshika, A
Matsubayashi, J
Mukai, K
机构
[1] Tokyo Med Univ, Dept Pediat, Shinjuku Ku, Tokyo 1600023, Japan
[2] Tokyo Med Univ, Dept Pathol, Tokyo 1600023, Japan
关键词
sudden infant death syndrome (SIDS); parainfluenza virus type 2 (PIV2); hemophagocytic syndrome (HPS);
D O I
10.1016/j.jinf.2003.10.002
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We report a child with Sudden Infant Death Syndrome (SIDS), aged 16 months. The histological findings of tonsils, spleen, and bone marrow revealed many hemophagocytic cells. Parainfluenza virus type 2 (PIV2) was cultured in the nasopharynx and detected by reverse-transcription (RT)-PCR in liver tissue and bone marrow. His laboratory data of elevated level of ferritin and IL-6 suggested hemophagocytic syndrome (HPS). It is suspected that PIV2 infection in infants is a risk factor for SIDS. (C) 2003 The British Infection Society. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:329 / 332
页数:4
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