Reversal of rocuronium-induced (1.2 mg kg-1) profound neuromuscular block by accidental high dose of sugammadex (40 mg kg-1)

被引：17

作者：

Molina, A. L.

de Boer, H. D.

Klimek, M.

Heeringa, M.

Klein, J.

机构：

[1] Radboud Univ Nijmegen, Med Ctr Nijmgen, Martini Hosp Groningen, Dept Anaesthesiol, NL-9700 RM Groningen, Netherlands

[2] Erasmus Univ, Med Ctr, Dept Anaesthesiol, Rotterdam, Netherlands

[3] NV Organon, Global Clin Dev, NL-5340 BH Oss, Netherlands

来源：

BRITISH JOURNAL OF ANAESTHESIA | 2007年 / 98卷 / 05期

关键词：

neuromuscular block; rocuronium; neuromuscular relaxant; sugammadex; reversal agent;

D O I：

10.1093/bja/aem057

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Sugammadex is the first selective relaxant binding agent and reverses rocuronium-induced neuromuscular block. A case is reported in which a patient accidentally received a high dose of sugammadex (40 mg kg(-1)) to reverse a rocuronium-induced (1.2 mg kg(-1)) profound neuromuscular block. A fast and efficient recovery from profound neuromuscular block was achieved and no adverse events or other safety concerns were reported.

引用

页码：624 / 627

页数：4

共 10 条

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