D-alanine piperazine-amides:: novel non-imidazole antagonists of the histamine H3 receptor

被引:6
|
作者
Faghih, R [1 ]
Phelan, K [1 ]
Esbenshade, TA [1 ]
Miller, TR [1 ]
Kang, CH [1 ]
Krueger, KM [1 ]
Yao, BB [1 ]
Fox, GB [1 ]
Bennani, YL [1 ]
Hancock, AA [1 ]
机构
[1] Abbott Labs, Neurosci Res, Global Pharmaceut Res & Dev, Abbott Pk, IL 60064 USA
关键词
Histamine;
D O I
10.1007/s000110300049
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:S47 / S48
页数:2
相关论文
共 50 条
  • [41] Novel human histamine H3 receptor antagonists
    Shah, C
    McAtee, L
    Breitenbucher, JG
    Rudolph, D
    Li, XB
    Lovenberg, TW
    Mazur, C
    Wilson, SJ
    Carruthers, NI
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2002, 12 (22) : 3309 - 3312
  • [42] A new class of potent non-imidazole H3 antagonists:: 2-aminoethylbenzofurans
    Cowart, M
    Pratt, JK
    Stewart, AO
    Bennani, YL
    Esbenshade, TA
    Hancock, AA
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2004, 14 (03) : 689 - 693
  • [43] Lack of cataleptogenic potentiation with non-imidazole H3 receptor antagonists reveals potential drug-drug interactions between imidazole-based H3 receptor antagonists and antipsychotic drugs
    Zhang, M
    Ballard, ME
    Pan, LP
    Roberts, S
    Faghih, R
    Cowart, M
    Esbenshade, TA
    Fox, GB
    Decker, MW
    Hancock, AA
    Rueter, LE
    BRAIN RESEARCH, 2005, 1045 (1-2) : 142 - 149
  • [44] Anxiolytic and antidepressant-like activities of the novel and potent non-imidazole histamine H3 receptor antagonist ST-1283
    Bahi, Amine
    Schwed, Johannes Stephan
    Walter, Miriam
    Stark, Holger
    Sadek, Bassem
    DRUG DESIGN DEVELOPMENT AND THERAPY, 2014, 8 : 627 - 637
  • [45] Histamine H3 receptor antagonists
    Tozer, MJ
    Kalindjian, SB
    EXPERT OPINION ON THERAPEUTIC PATENTS, 2000, 10 (07) : 1045 - 1055
  • [46] Anticonvulsant evaluation of novel non-imidazole histamine H3R antagonists in different convulsion models in rats
    Alachkar, Alaa
    Latacz, Gniewomir
    Siwek, Agata
    Lubelska, Annamaria
    Honkisz, Ewelina
    Grybos, Anna
    Lazewska, Dorota
    Handzlik, Jadwiga
    Stark, Holger
    Kiec-Kononowicz, Katarzyna
    Sadek, Bassem
    PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2018, 170 : 14 - 24
  • [47] PIPERAZINE DERIVATIVES AS A NOVEL, ACTIVE HISTAMINE H3 RECEPTOR LIGANDS
    Szczepanska, K.
    Karcz, T.
    Mogilski, S.
    Kuder, K. J.
    Hagenow, S.
    Kotanska, M.
    Stark, H.
    Kiec-Kononowicz, K.
    INFLAMMATION RESEARCH, 2018, 67 : S30 - S30
  • [48] Procognitive potential of novel aryl and heteroaryl amides as potent and selective histamine H3 receptor antagonists
    Nirogi, Ramakrishna
    Shinde, Anil
    Deshpande, Amol
    Dwarampudi, Adireddy
    Gangadasari, Pamuleti Narasimhareddy
    Gudla, Parandhama
    Kota, Laxman
    Gampa, Muralimohan
    Kodru, Padmavathi
    Tiriveedhi, Vinaykumar
    Saraf, Sangram K.
    Shaik, Mohammad
    Badange, Rajeshkumar
    Bojja, Kumar
    Balasubramaniam, Suresh
    Faheem, Mohammed
    Kandikere, Vishwottam
    Jayarajan, Pradeep
    Muddana, Nageswararao
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 246
  • [49] Synthesis and SAR of novel histamine H3 receptor antagonists
    Jesudason, Cynthia D.
    Beavers, Lisa S.
    Cramer, Jeffrey W.
    Dill, Joelle
    Finley, Don R.
    Lindsley, Craig W.
    Stevens, F. Craig
    Gadski, Robert A.
    Oldham, Samuel W.
    Pickard, R. Todd
    Siedem, Christopher S.
    Sindelar, Dana K.
    Singh, Ajay
    Watson, Brian M.
    Hipskind, Philip A.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (13) : 3415 - 3418
  • [50] Discovery of a New Class of Non-imidazole Oxazoline-Based Histamine H3 Receptor (H3R) Inverse Agonists
    Celanire, Sylvain
    Wijtmans, Maikel
    Christophe, Bernard
    Collart, Philippe
    de Esch, Iwan
    Dassesse, Donald
    Delaunoy, Christel
    Denonne, Frederic
    Durieu, Veronique
    Gelens, Edith
    Gillard, Michel
    Lallemand, Benedicte
    Lamberty, Yves
    Lebon, Florence
    Nicolas, Jean-Marie
    Quere, Luc
    Snip, Erwin
    Vanbellinghen, Alain
    Van Houtvin, Nathalie
    Verbois, Valerie
    Timmerman, Henk
    Talaga, Patrice
    Leurs, Rob
    Provins, Laurent
    CHEMMEDCHEM, 2009, 4 (07) : 1063 - 1068