Impact of Baseline Tuberculin Skin Test and Isoniazid Chemoprophylaxis on Subsequent Quantiferon-TB Gold In-Tube Performance in Young Children Assessed After Tuberculosis Contact in Catalonia

被引：3

作者：

Velasco-Arnaiz, Eneritz ^{[1
,2
]}

Soriano-Arandes, Antoni ^{[3
]}

Espiau, Maria ^{[3
]}

Altet, Neus ^{[1
,3
]}

Fortuny, Claudia ^{[2
,4
,5
]}

Monsonis, Manuel ^{[6
]}

Tebruegge, Marc ^{[7
,8
,9
,10
,11
]}

Noguera-Julian, Antoni ^{[1
,2
,4
,5
]}

机构：

[1] Hosp St Joan Deu, Malalties Infeccioses & Resposta Inflamatoria Sis, Inst Recerca Pediat, Unitat Infecc,Serv Pediat, Barcelona, Spain

[2] Univ Barcelona, Dept Pediat, Barcelona, Spain

[3] Hosp Univ Vall dHebron, Vall dHebron Res Inst, Pediat Infect Dis & Immunodeficiencies Unit, Barcelona, Spain

[4] CIBERESP, CIBER Epidemiol & Salud Publ, Madrid, Spain

[5] RITIP, Madrid, Spain

[6] Hosp St Joan Deu, Serv Microbiol, Barcelona, Spain

[7] Univ Southampton, Fac Med, Acad Unit Clin & Expt Sci, Southampton, Hants, England

[8] Univ Southampton, Global Hlth Res Inst, Southampton, Hants, England

[9] Guys & St Thomas NHS Fdn Trust, Evelina London Childrens Hosp, Dept Paediat Infect Dis & Immunol, London, England

[10] UCL, Great Ormond St Hosp Inst Child Hlth, London, England

[11] Univ Melbourne, Dept Paediat, Parkville, Vic, Australia

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2020年 / 39卷 / 02期

关键词：

infant; interferon-gamma release assay; isoniazid; tuberculin skin test; boosting; GAMMA RELEASE ASSAYS; DIAGNOSIS; GUIDELINES; INFECTION; RESPONSES; DISEASE; LATENT;

D O I：

10.1097/INF.0000000000002517

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We investigated the impact of baseline tuberculin skin tests (TSTs) and preventive isoniazid chemoprophylaxis on subsequent QuantiFERON-TB Gold In-Tube (QFT-GIT) assays performed after a 10- to 12-week window period in 114 children <5 years of age. Previous TSTs and chemoprophylaxis had no impact on the magnitude of subsequent antigen-induced responses in QFT-GIT. Furthermore, previous TSTs did not induce conversion from a negative to a positive QFT-GIT result.

引用

页码：E22 / E25

页数：4

共 21 条

[1] Predicting the Development of Tuberculosis with the Tuberculin Skin Test and QuantiFERON Testing [J].

Altet, Neus ;

Dominguez, Jose ;

de Souza-Galvao, Maria-Luiza ;

Angeles Jimenez-Fuentes, M. ;

Mila, Celia ;

Solsona, Jordi ;

Soriano-Arandes, Antonio ;

Latorre, Irene ;

Lara, Elisa ;

Cantos, Adela ;

Dolores Ferrer, Maria ;

Orcau, Angels ;

Ruiz-Manzano, Juan ;

Cayla, Joan .

ANNALS OF THE AMERICAN THORACIC SOCIETY, 2015, 12 (05) :680-688

[2] Performance of the QuantiFERON®-TB Gold In-Tube assay in tuberculin skin test converters: a prospective cohort study [J].

Castellanos, M. E. ;

Kirimunda, S. ;

Martinez, L. ;

Quach, T. ;

Woldu, H. ;

Kakaire, R. ;

Handel, A. ;

Zalwango, S. ;

Kiwanuka, N. ;

Whalen, C. C. .

INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, 2018, 22 (09) :1000-+

[3] The impact of anti-tuberculous antibiotics and corticosteroids on cytokine production in QuantiFERON-TB Gold In Tube assays [J].

Clifford, Vanessa ;

Zufferey, Christel ;

Germano, Susie ;

Ryan, Norbert ;

Leslie, David ;

Street, Alan ;

Denholm, Justin ;

Tebruegge, Marc ;

Curtis, Nigel .

TUBERCULOSIS, 2015, 95 (03) :343-349

[4] Interferon-gamma release assays have suboptimal sensitivity in both latent and active tuberculosis [J].

Goetzinger, F. ;

Burkhardt, I. ;

Villanueva, P. ;

Clifford, V. ;

Curtis, N. ;

Tebruegge, M. .

INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, 2019, 23 (06) :766-767

[5] Temporal Dynamics of Interferon Gamma Responses in Children Evaluated for Tuberculosis [J].

Herrmann, Jean-Louis ;

Belloy, Marie ;

Porcher, Raphael ;

Simonney, Nancy ;

Aboutaam, Rola ;

Lebourgeois, Muriel ;

Gaudelus, Joel ;

De LosAngeles, Laure ;

Chadelat, Katarina ;

Scheinmann, Pierre ;

Beydon, Nicole ;

Fauroux, Brigitte ;

Bingen, Martine ;

Terki, Mustapha ;

Barraud, Dominique ;

Cruaud, Philippe ;

Offredo, Catherine ;

Ferroni, Agnes ;

Berche, Patrick ;

Moissenet, Didier ;

Vuthien, Hoang ;

Doit, Catherine ;

Bingen, Edouard ;

Lagrange, Philippe Henri .

PLOS ONE, 2009, 4 (01)

[6] Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and Children [J].

Lewinsohn, David M. ;

Leonard, Michael K. ;

LoBue, Philip A. ;

Cohn, David L. ;

Daley, Charles L. ;

Desmond, Ed ;

Keane, Joseph ;

Lewinsohn, Deborah A. ;

Loeffler, Ann M. ;

Mazurek, Gerald H. ;

O'Brien, Richard J. ;

Pai, Madhukar ;

Richeldi, Luca ;

Salfinger, Max ;

Shinnick, Thomas M. ;

Sterling, Timothy R. ;

Warshauer, David M. ;

Woods, Gail L. .

CLINICAL INFECTIOUS DISEASES, 2017, 64 (02) :E1-E33

[7] Effect of tuberculin skin testing on a Mycobacterium tuberculosis-specific interferon-γ assay [J].

Leyten, E. M. S. ;

Prins, C. ;

Bossink, A. W. J. ;

Thijsen, S. ;

Ottenhoff, T. H. M. ;

van Dissel, J. T. ;

Arend, S. M. .

EUROPEAN RESPIRATORY JOURNAL, 2007, 29 (06) :1212-1216

[8]

Marais BJ, 2004, INT J TUBERC LUNG D, V8, P392

[9]

Mellado-Pena MJ, 2018, AN PEDIAT BARC, V88, p52e1

[10] Evidence for boosting Mycobacterium tuberculosis-specific IFN-γ responses at 6 weeks following tuberculin skin testing [J].

Naseer, A. ;

Naqvi, S. ;

Kampmann, B. .

EUROPEAN RESPIRATORY JOURNAL, 2007, 29 (06) :1282-1283

← 1 2 3 →