Solvent-free microwave-assisted Meyers' lactamization

被引：28
|
作者：
Jida, Mouhamad [1 ,2 ]
Deprez-Poulain, Rebecca [1 ,2 ]
Malaquin, Sandra [1 ,2 ]
Roussel, Pascal [2 ,3 ]
Agbossou-Niedercorn, Francine [2 ,3 ]
Deprez, Benoit [1 ,2 ]
Laconde, Guillaume [1 ,2 ]
机构：
[1] Univ Lille Nord France, INSERM, Fac Pharm, U761, F-59006 Lille, France
[2] PRIM, F-59000 Lille, France
[3] USTL, CNRS, Unite Catalyse & Chim Solide, UMR 8181, F-59655 Villeneuve Dascq, France
来源：
GREEN CHEMISTRY | 2010年 / 12卷 / 06期
关键词：
ENANTIOSELECTIVE SYNTHESIS; ASYMMETRIC-SYNTHESIS; BICYCLIC LACTAMS; STEREOSELECTIVE-SYNTHESIS; KINETIC RESOLUTION; PIPERIDINES; MOLECULES; AUXILIARY; CORE;
D O I：
10.1039/b924111f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Microwave solvent-free conditions developed for Meyers' lactamization, a typical bielectrophile-binucleophile reaction that produces quaternary centers in a stereoselective manner, give access to Meyers' chiral lactams in good yield and high diastereoselectivity in short times.
引用
收藏
页码：961 / 964
页数：4
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