Synthesis of two diastereomeric C1-C22 fragments of spirastrellolide A

被引：44

作者：

Paterson, Ian ^{[1
]}

Anderson, Edward A. ^{[1
]}

Dalby, Stephen M. ^{[1
]}

Genovino, Julien ^{[1
]}

Lim, Jong Ho ^{[1
]}

Moessner, Christian ^{[1
]}

机构：

[1] Univ Cambridge, Chem Lab, Cambridge CB2 1EW, England

来源：

CHEMICAL COMMUNICATIONS | 2007年 / 18期

关键词：

D O I：

10.1039/b700827a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The optimisation of a synthetic strategy towards the ABC segment of the cytotoxic macrolide spirastrellolide A is reported, together with its application to the synthesis of two diastereomeric C-1 - C-22 fragments for stereochemical correlation purposes with a putative spirastrellolide degradation product.

引用

收藏

页码：1852 / 1854

页数：3

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