Heck-type hydroarylations and 1,3-dipolar cycloaddition reactions of new tricyclic hydrazones

被引：8

作者：

Gul, Melek ^{[1
]}

Ocal, Nuket ^{[1
]}

机构：

[1] Yildiz Tech Univ, Fac Art & Sci, Dept Chem, TR-34210 Istanbul, Turkey

来源：

CANADIAN JOURNAL OF CHEMISTRY | 2010年 / 88卷 / 04期

关键词：

tricyclic hydrazone; reductive Heck reactions; C-C coupling; nitrile oxides; isoxazolines; IRON CHELATORS; CHEMISTRY; EPIBATIDINE;

D O I：

10.1139/V09-179

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The C-C coupling of the new tricyclic hydrazones 3-7 with aryl and heteroaryl halides gave under reductive Heck conditions the tricyclic 1-(arylideneamino)pyrolidine-2,5-diones 8-11a, 9-11b, 10c, and 12. The [3+2] cycloadditions of 3-7 with p-chlorophenyl nitrile oxide (13) yielded the bridged isoxazoline derivatives 14-18 with potential biological activity.

引用

页码：323 / 330

页数：8

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