Upholding a role for EMT in breast cancer metastasis

被引：257

作者：

Ye, Xin ^{[1
,2
]}

Brabletz, Thomas ^{[3
]}

Kang, Yibin ^{[4
]}

Longmore, Gregory D. ^{[5
,6
]}

Angela Nieto, M. ^{[7
,8
]}

Stanger, Ben Z. ^{[9
,10
]}

Yang, Jing ^{[11
]}

Weinberg, Robert A. ^{[1
,2
,12
]}

机构：

[1] Whitehead Inst Biomed Res, 9 Cambridge Ctr, Cambridge, MA 02142 USA

[2] Ludwig MIT Ctr Mol Oncol, Cambridge, MA 02142 USA

[3] FAU Univ Erlangen Nuernberg, Nikolaus Fiebiger Ctr Mol Med, Expt Med 1, D-91054 Erlangen, Germany

[4] Princeton Univ, Dept Mol Biol, Princeton, NJ 08544 USA

[5] Washington Univ, Dept Med, ICCE Inst, St Louis, MO 63110 USA

[6] Washington Univ, Dept Cell Biol & Physiol, ICCE Inst, St Louis, MO 63110 USA

[7] CSIC, Inst Neurociencias, Alacant, Spain

[8] Univ Miguel Hernandez, Alacant, Spain

[9] Univ Penn, Perelman Sch Med, Abramson Family Canc Res Inst, Dept Med, Philadelphia, PA 19104 USA

[10] Univ Penn, Perelman Sch Med, Abramson Family Canc Res Inst, Dept Cell & Dev Biol, Philadelphia, PA 19104 USA

[11] Univ Calif San Diego, Dept Pharmacol, Moores Canc Ctr, 3855 Hlth Sci Dr,MC0819, La Jolla, CA 92093 USA

[12] MIT, Dept Biol, 77 Massachusetts Ave, Cambridge, MA 02142 USA

来源：

NATURE | 2017年 / 547卷 / 7661期

关键词：

EPITHELIAL-MESENCHYMAL TRANSITION; TRANSCRIPTION FACTOR SNAIL; TUMOR-INITIATING CELLS; E-CADHERIN EXPRESSION; COLONIZATION; REPRESSION;

D O I：

10.1038/nature22816

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

[No abstract available]

引用

页码：E1 / E4

页数：4

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