Novel BRAF alteration in desmoplastic infantile ganglioglioma with response to targeted therapy

被引:13
作者
Blessing, Melissa M. [1 ]
Blackburn, Patrick R. [1 ]
Balcom, Jessica R. [1 ]
Krishnan, Chandra [3 ]
Harrod, Virginia L. [4 ]
Zimmermann, Michael T. [5 ]
Fritcher, Emily G. Barr [1 ]
Zysk, Christopher D. [1 ]
Jackson, Rory A. [1 ]
Nair, Asha A. [2 ]
Jenkins, Robert B. [1 ]
Halling, Kevin C. [1 ]
Kipp, Benjamin R. [1 ]
Ida, Cristiane M. [1 ]
机构
[1] Mayo Clin, Dept Lab Med & Pathol, 200 First St SW, Rochester, MN 55905 USA
[2] Mayo Clin, Dept Hlth Sci Res, Rochester, MN USA
[3] Dell Childrens Med Ctr, Dept Pathol, Austin, TX USA
[4] Dell Childrens Med Ctr, Neurooncol Div, Austin, TX USA
[5] Med Coll Wisconsin, Genom Sci & Precis Med Ctr, Bioinformat Res & Dev Lab, Milwaukee, WI 53226 USA
关键词
BRAF; DIG; MAPK; Targeted therapy; MAPK PATHWAY ACTIVATION; LOW-GRADE GLIOMAS; GENETIC ALTERATIONS; ASTROCYTOMAS; EXPRESSION; TUMOR;
D O I
10.1186/s40478-018-0622-1
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
[No abstract available]
引用
收藏
页数:4
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