Percentage non-caeruloplasmin bound copper

被引：10

作者：

Twomey, Patrick J.

Wierzblcki, Anthony S.

House, Ivan M.

Viljoen, Adie

Reynolds, Timothy M.

机构：

[1] Ipswich Hosp, Dept Clin Biochem, Ipswich IP4 5PD, Suffolk, England

[2] St Thomas Hosp, Dept Chem Pathol, London SE1 7EH, England

[3] Guys & St Thomas Hosp Trust, Med Toxicol Unit Lab, London SE14 5ER, England

[4] Lister Hosp, Dept Clin Biochem, Stevenage SG1 4UB, Herts, England

[5] Queens Hosp, Dept Chem Pathol, Burton Upon Trent DE13 0RB, England

来源：

CLINICAL BIOCHEMISTRY | 2007年 / 40卷 / 9-10期

关键词：

copper; caeruloplasmin; calculation; Wilson's disease; percent free copper;

D O I：

10.1016/j.clinbiochem.2007.04.002

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Objectives: To compare percentage non-caeruloplasmin bound copper (%NCC) to generally accepted values. Design and methods: Using data for 338 normal individual patients, we calculated the % NCC. Results: The %NCC ranged (median) from -59.75% to 51.98% (8.75%) respectively. The non-parametric reference interval was -23.44% to 22.99% with 43.8% of the %NCC values > 10%. Conclusions: We found the %NCC to be higher than generally accepted. This may be due to uncertainty from precision, bias and specificity. (c) 2007 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

引用

页码：749 / 750

页数：2

共 11 条

[1] Effects of storage at-20°C on ischaemia-modified albumin results [J].