The pentatricopeptide repeat protein MEF26 participates in RNA editing in mitochondrial cox3 and nad4 transcripts

被引：9

作者：

Arenas-M., Anita ^{[1
]}

Zehrmann, Anja ^{[2
]}

Moreno, Sebastian ^{[1
]}

Takenaka, Mizuki ^{[2
]}

Jordana, Xavier ^{[1
]}

机构：

[1] Pontificia Univ Catolica Chile, Fac Ciencias Biol, Dept Mol Genet & Microbiol, Santiago, Chile

[2] Univ Ulm, D-89069 Ulm, Germany

来源：

MITOCHONDRION | 2014年 / 19卷

关键词：

PPR protein; RNA editing factor; Plant mitochondria; Pentatricopeptide repeat protein; cox3; nad4; CIS-ACTING ELEMENTS; PPR PROTEIN; ARABIDOPSIS-THALIANA; DYW PROTEIN; MULTIPLE SITES; COMPLEX-I; RECOGNITION; SEQUENCES; GENE; IDENTIFICATION;

D O I：

10.1016/j.mito.2014.08.006

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In angiosperms most members of the large nuclear-encoded family of pentatricopeptide repeat (PPR) proteins are predicted to play relevant roles in the maturation of organellar RNAs. Here we report the novel Mitochondrial Editing Factor 26, a DYW-PPR protein involved in RNA editing at two sites. While at one site, cox3-311, editing is abolished in the absence of MEF26, the other site, nad4-166, is still partially edited. These sites share similar cis-elements and application of the recently proposed amino acid code for RNA recognition by PPR proteins ranks them at first and second positions of the most probable targets. (C) 2014 Elsevier B.V. and Mitochondria Research Society. All rights reserved.

引用

页码：126 / 134

页数：9

共 61 条

[1] Contiguous RNA editing sites in the mitochondrial nad1 transcript of Arabidopsis thaliana are recognized by different proteins [J].

Arenas-M, Anita ;

Takenaka, Mizuki ;

Moreno, Sebastian ;

Gomez, Isabel ;

Jordana, Xavier .

FEBS LETTERS, 2013, 587 (07) :887-891

[2] Extensive feature detection of N-terminal protein sorting signals [J].

Bannai, H ;

Tamada, Y ;

Maruyama, O ;

Nakai, K ;

Miyano, S .

BIOINFORMATICS, 2002, 18 (02) :298-305

[3] Crystal structure of the entire respiratory complex I [J].

Baradaran, Rozbeh ;

Berrisford, John M. ;

Minhas, Gurdeep S. ;

Sazanov, Leonid A. .

NATURE, 2013, 494 (7438) :443-448

[4] Pentatricopeptide Repeat Proteins in Plants [J].

Barkan, Alice ;

Small, Ian .

ANNUAL REVIEW OF PLANT BIOLOGY, VOL 65, 2014, 65 :415-+

[5] A Combinatorial Amino Acid Code for RNA Recognition by Pentatricopeptide Repeat Proteins [J].

Barkan, Alice ;

Rojas, Margarita ;

Fujii, Sota ;

Yap, Aaron ;

Chong, Yee Seng ;

Bond, Charles S. ;

Small, Ian .

PLOS GENETICS, 2012, 8 (08)

[6] RIP1, a member of an Arabidopsis protein family, interacts with the protein RARE1 and broadly affects RNA editing [J].

Bentolila, Stephane ;

Heller, Wade P. ;

Sun, Tao ;

Babina, Arianne M. ;

Friso, Giulia ;

van Wijk, Klaas J. ;

Hanson, Maureen R. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (22) :E1453-E1461

[7] Natural Variation in Arabidopsis Leads to the Identification of REME1, a Pentatricopeptide Repeat-DYW Protein Controlling the Editing of Mitochondrial Transcripts [J].

Bentolila, Stephane ;

Knight, Walter ;

Hanson, Maureen .

PLANT PHYSIOLOGY, 2010, 154 (04) :1966-1982

[8] OTP70 is a pentatricopeptide repeat protein of the E subgroup involved in splicing of the plastid transcript rpoC1 [J].

Chateigner-Boutin, Anne-Laure ;

des Francs-Small, Catherine Colas ;

Delannoy, Etienne ;

Kahlau, Sabine ;

Tanz, Sandra K. ;

de Longevialle, Andeol Falcon ;

Fujii, Sota ;

Small, Ian .

PLANT JOURNAL, 2011, 65 (04) :532-542

[9] Sequences directing C to U editing of the plastid psbL mRNA are located within a 22 nucleotide segment spanning the editing site [J].

Chaudhuri, S ;

Maliga, P .

EMBO JOURNAL, 1996, 15 (21) :5958-5964

[10] Different patterns in the recognition of editing sites in plant mitochondria [J].

Choury, D ;

Farré, JC ;

Jordana, X ;

Araya, A .

NUCLEIC ACIDS RESEARCH, 2004, 32 (21) :6397-6406

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