Optic neuropathy following radiotherapy for Cushing's disease: case report and literature review

被引：10

作者：

Ballian, Nikiforos ^{[3
]}

Androulakis, Ioannis I. ^{[1
]}

Chatzistefanou, Kilo ^{[2
]}

Samara, Christianna ^{[4
]}

Tsiveriotis, Konstantinos ^{[5
]}

Kaltsas, Gregory A. ^{[5
]}

机构：

[1] Gen Hosp Athens G Gennimatas, Dept Endocrinol, Athens 11562, Greece

[2] Gen Hosp Athens G Gennimatas, Dept Ophthalmol, Athens 11562, Greece

[3] Univ Wisconsin, Dept Surg, Madison, WI USA

[4] Gen Hosp Athens G Gennimatas, Dept Radiol, Athens 11562, Greece

[5] Univ Athens, Dept Pathophysiol, Athens, Greece

来源：

HORMONES-INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM | 2010年 / 9卷 / 03期

关键词：

Hyperbaric oxygen; Optic neuropathy; Pituitary adenoma; Radiotherapy; HYPERBARIC-OXYGEN THERAPY; POSTOPERATIVE RADIATION-THERAPY; PITUITARY-ADENOMA; STEREOTACTIC RADIOSURGERY; IRRADIATION; INJURY; SURGERY; NERVES;

D O I：

10.1007/BF03401278

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Radiation-induced optic neuropathy is a rare adverse effect of radiotherapy applied for the treatment of pituitary adenomas. We report a patient with a recurrent adrenocorticotrophin secreting pituitary adenoma who received external beam irradiation after failing surgical and medical therapy. Sixteen months after radiotherapy, the patient was presented with declining visual acuity, and radiation-induced optic neuropathy was diagnosed. Despite treatment with glucocorticoids and hyperbaric oxygen, her vision did not improve. The pathophysiology, prevention and treatment of radiation-induced optic neuropathy, including the efficacy of hyperbaric oxygen therapy are reviewed.

引用

页码：269 / 273

页数：5

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