Coronary artery calcification revisited

被引:27
作者
Ehara, Shoichi
Kobayashi, Yoshiki
Yoshiyama, Minoru
Ueda, Makiko
Yoshikawa, Junichi
机构
[1] Osaka City Univ, Grad Sch Med, Dept Internal Med & Cardiol, Abeno Ku, Osaka 5458585, Japan
[2] Osaka City Univ, Grad Sch Med, Dept Pathol, Osaka 5458585, Japan
[3] Osaka Ekisaikai Hosp, Osaka, Japan
关键词
coronary disease; remodeling; ultrasonics; calcium; myocardial infarction;
D O I
10.5551/jat.13.31
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Calcification is a common finding in human coronary arteries. However, there is conflicting evidence for a link between calcification and plaque instability. Current intravascular ultrasound (IVUS) technology allows a definitive detection of the calcification and measurement of the vessel wall. Using preinterventional IVUS images, we clarified that in patients with acute myocardial infarction, small "spotty" calcifications prevailed, associated with a fibrofatty plaque and positive remodeling. Conversely, in patients with stable angina pectoris, extensive calcification was frequent. IVUS allows the detection of vulnerable plaques in coronary arteries, by identifying not only a large lipid core and positive remodeling, but also a spotty pattern of calcification.
引用
收藏
页码:31 / 37
页数:7
相关论文
共 34 条
[1]   Prediction of coronary events with electron beam computed tomography [J].
Arad, Y ;
Spadaro, LA ;
Goodman, K ;
Newstein, D ;
Guerci, AD .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2000, 36 (04) :1253-1260
[2]   Relationship of clinical presentation and calcification of culprit coronary artery stenoses [J].
Beckman, JA ;
Ganz, J ;
Creager, MA ;
Ganz, P ;
Kinlay, S .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2001, 21 (10) :1618-1622
[3]   Morphological predictors of arterial remodeling in coronary atherosclerosis [J].
Burke, AP ;
Kolodgie, FD ;
Farb, A ;
Weber, D ;
Virmani, R .
CIRCULATION, 2002, 105 (03) :297-303
[4]   Effect of risk factors on the mechanism of acute thrombosis and sudden coronary death in women [J].
Burke, AP ;
Farb, A ;
Malcom, GT ;
Liang, YH ;
Smialek, J ;
Virmani, R .
CIRCULATION, 1998, 97 (21) :2110-2116
[5]   Pathophysiology of calcium deposition in coronary arteries [J].
Burke, AP ;
Weber, DK ;
Kolodgie, FD ;
Farb, A ;
Taylor, AJ ;
Virmani, R .
HERZ, 2001, 26 (04) :239-244
[6]   DISTRIBUTION OF CIRCUMFERENTIAL STRESS IN RUPTURED AND STABLE ATHEROSCLEROTIC LESIONS - A STRUCTURAL-ANALYSIS WITH HISTOPATHOLOGICAL CORRELATION [J].
CHENG, GC ;
LOREE, HM ;
KAMM, RD ;
FISHBEIN, MC ;
LEE, RT .
CIRCULATION, 1993, 87 (04) :1179-1187
[7]   ISCHEMIA-RELATED LESION CHARACTERISTICS IN PATIENTS WITH STABLE OR UNSTABLE ANGINA - A STUDY WITH INTRACORONARY ANGIOSCOPY AND ULTRASOUND [J].
DEFEYTER, PJ ;
OZAKI, Y ;
BAPTISTA, J ;
ESCANED, J ;
DIMARIO, C ;
DEJAEGERE, PPT ;
SERRUYS, PW ;
ROELANDT, JRTC .
CIRCULATION, 1995, 92 (06) :1408-1413
[8]   MECHANISM OF CALCIFICATION IN ATHEROSCLEROSIS [J].
DEMER, LL ;
WATSON, KE ;
BOSTROM, K .
TRENDS IN CARDIOVASCULAR MEDICINE, 1994, 4 (01) :45-49
[9]   Vascular calcification and osteoporosis: inflammatory responses to oxidized lipids [J].
Demer, LL .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2002, 31 (04) :737-741
[10]   Spotty calcification typifies the culprit plaque in patients with acute myocardial infarction - An intravascular ultrasound study [J].
Ehara, S ;
Kobayashi, Y ;
Yoshiyama, M ;
Shimada, K ;
Shimada, Y ;
Fukuda, D ;
Nakamura, Y ;
Yamashita, H ;
Yamagishi, H ;
Takeuchi, K ;
Naruko, T ;
Haze, K ;
Becker, AE ;
Yoshikawa, J ;
Ueda, M .
CIRCULATION, 2004, 110 (22) :3424-3429