Pharyngeal carriage of group C and group G streptococci and acute rheumatic fever in an Aboriginal population

被引：78

作者：

Haidan, A

Talay, SR

Rohde, M

Sriprakash, KS

Currie, BJ

Chhatwal, GS ^{[1
]}

机构：

[1] GBF German Res Ctr Biotechnol, Dept Microbiol Pathogenesis & Vaccine Res, D-38124 Braunschweig, Germany

[2] Menzies Sch Hlth Res, Darwin, NT, Australia

来源：

LANCET | 2000年 / 356卷 / 9236期

关键词：

D O I：

10.1016/S0140-6736(00)02765-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) represent an autoimmune response to group A streptococcal pharyngitis, In the Aboriginal population of the Northern Territory of Australia, some of the highest rates of ARF in the world have been reported, although throat carriage rates of group A streptococcus in this population are extremely low and symptomatic group A streptococcal pharyngitis is uncommon; by contrast, carriage rates of group C and G streptococci are high, Therefore, we questioned the involvement of these groups in ARF and showed that they have the potential to elicit an autoimmune response that may trigger ARF.

引用

页码：1167 / 1169

页数：3

共 5 条

[1] Group A streptococcus, pyoderma, and rheumatic fever [J].