Effects of bioactive constituents in functional cocoa products on cardiovascular health in humans

被引：45

作者：

Sarria, Beatriz ^{[1
]}

Martinez-Lopez, Sara ^{[1
]}

Luis Sierra-Cinos, Jose ^{[2
]}

Garcia-Diz, Luis ^{[2
]}

Goya, Luis ^{[1
]}

Mateos, Raquel ^{[1
]}

Bravo, Laura ^{[1
]}

机构：

[1] CSIC, Inst Food Sci Technol & Nutr ICTAN, Dept Metab & Nutr, Madrid 28040, Spain

[2] Univ Complutense Madrid, Sch Pharm, Dept Nutr & Bromathol 1, E-28040 Madrid, Spain

来源：

FOOD CHEMISTRY | 2015年 / 174卷

关键词：

Soluble cocoa products; Dietary fibre; Polyphenols; Methylxanthines; Cardiovascular health; Hypoglycemic; Inflammation; RISK-FACTORS; HDL-CHOLESTEROL; DIETARY FIBER; SYSTEMIC INFLAMMATION; DARK CHOCOLATE; WHOLE GRAINS; CONSUMPTION; MARKERS; BRAN; METAANALYSIS;

D O I：

10.1016/j.foodchem.2014.11.004

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Cocoa manufacturers are producing novel products increasing polyphenols, methylxanthines or dietary fibre to improve purported health benefits. We attempt to explain the contribution of cocoa bioactive compounds to cardiovascular effects observed in previous studies, placing particular emphasis on methylxanthines. We focused on a soluble cocoa product rich in dietary fibre (DFCP) and a product rich in polyphenols (PPCP). Effects of regularly consuming DFCP (providing daily 10.17 g, 43.8 mg and 168.6 mg of total-dietary-fibre, flavanols and methylxanthines, respectively) as well as PPCP (providing daily 3.74 g, 45.3 mg and 109.8 mg of total-dietary-fibre, flavanols and methylxanthines, respectively) on cardiovascular health were assessed in two controlled, cross-over studies in free-living normocholesterolemic and moderately hypercholesterolemic subjects. Both products increased HDL-cholesterol concentrations, whereas only DFCP decreased glucose and IL-1 beta levels in all subjects. Flavanols appeared to be responsible for the increase in HDL-cholesterol, whereas insoluble-dietary-fibre and theobromine in DFCP were associated with the hypoglycemic and anti-inflammatory effects observed. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：214 / 218

页数：5

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