Derivatives of 4H-pyran-4-one with the atom of sulfur in the side chain

被引:0
作者
Uher, M [1 ]
Kyselicova, L
Rajniakova, O
Hudecova, D
Bransova, J
Brtko, J
机构
[1] Slovak Univ Technol Bratislava, Fac Chem Technol, Dept Organ Chem, SK-81237 Bratislava, Slovakia
[2] Slovak Univ Technol Bratislava, Fac Chem Technol, Dept Biochem & Microbiol, SK-81237 Bratislava, Slovakia
[3] Slovak Acad Sci, Inst Expt Endocrinol, SK-83306 Bratislava, Slovakia
关键词
KOJIC ACID-DERIVATIVES;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Presented study investigates the 5-hydroxy-2-(alkyl/arylthiomethyl)-4H-pyran-4-ones preparation as well as their oxidation to appropriate sulfones. 5-Substituted 2-arylsulfomethyl-4H-pyran-4-ones were also prepared by the reaction of chloro- or bromokojic acid with the sodium salts of arylsulfonic acids. Thiocyanato, mesyl, and tosyl derivatives of kojic acid were prepared as well. The structures of the prepared derivatives of 4H-pyran-4-ones were confirmed, by IR, H-1 NMR, and mass spectral data. Their antimicrobial activity was determined as well.
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收藏
页码:421 / 426
页数:6
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