Plant Polyphenol-Assisted Green Synthesis of Hollow CoPt Alloy Nanoparticles for Dual-Modality Imaging Guided Photothermal Therapy

被引：60

作者：

Song, Xiao-Rong ^{[1
]}

Yu, Shu-Xian ^{[1
]}

Jin, Gui-Xiao ^{[1
]}

Wang, Xiaoyong ^{[2
]}

Chen, Jianzhong ^{[1
]}

Li, Juan ^{[1
]}

Liu, Gang ^{[2
]}

Yang, Huang-Hao ^{[1
]}

机构：

[1] Fuzhou Univ, Coll Chem, Key Lab Anal & Detect Technol Food Safety,MOE, State Key Lab Photocatalysis Energy & Environm, Fuzhou 350108, Peoples R China

[2] Xiamen Univ, Sch Publ Hlth, Ctr Mol Imaging & Translat Med, State Key Lab Mol Vaccinol & Mol Diagnost, Xiamen 361005, Peoples R China

来源：

SMALL | 2016年 / 12卷 / 11期

基金：

中国国家自然科学基金;

关键词：

COPPER SULFIDE NANOPARTICLES; BIOMEDICAL APPLICATIONS; THERANOSTIC PLATFORM; CARBON NANOTUBES; CONTRAST AGENT; GRAPHENE OXIDE; SHAPE CONTROL; NANOCRYSTALS; NANOSPHERES; COMBINATION;

D O I：

10.1002/smll.201503250

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Theranostic nanomedicines that integrate diagnostic and therapeutic moieties into a single nanoscale platform are playing an increasingly important role in fighting cancer. Here, a facile and green synthetic strategy for hollow CoPt alloy nanoparticles (HCPA-NPs) using plant polyphenols as assisted agents is reported for the first time. This novel strategy enables size-controlled synthesis of HCPA-NPs through the control of the molecular sizes of polyphenols. It is also a versatile strategy for synthesizing other hollow alloy nanoparticles with various metal compositions due to the diverse metal-chelating ability of the polyphenols. Further studies show that HCPA-NPs have good biocompatibility and can be successfully implemented for magnetic resonance and photoacoustic dual-modal imaging guided photothermal therapy. This work brings new insights for the green synthesis of hollow nanoparticles and extends these biocompatible nanoparticles for theranostic applications.

引用

页码：1506 / 1513

页数：8

共 52 条

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