Case of livedoid vasculopathy with extensive dermal capillary thrombi

被引:4
作者
Shimizu, Akira [1 ]
Tamura, Atsushi [1 ]
Yamanaka, Masayoshi [1 ]
Amano, Hiroo [1 ]
Nagai, Yayoi [1 ]
Ishikawa, Osamu [1 ]
机构
[1] Gunma Univ, Grad Sch Med, Dept Dermatol, Maebashi, Gunma 371, Japan
关键词
livedo reticularis; livedoid vasculopathy; thrombogenic factors; PHOSPHATIDYLSERINE-PROTHROMBIN COMPLEX; HIGH-TITER; VASCULITIS; AUTOANTIBODIES; MUTATION;
D O I
10.1111/j.1346-8138.2009.00753.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Livedoid vasculopathy (LV) is thought to be a thrombogenic disorder. Here, we report a case of LV presenting livedo reticularis with leg ulcers clinically and many thrombogenic cutaneous vessels histologically. These features strongly suggested the presence of thrombogenic factors involved with the development of the lesions. After examination of various possible thrombogenic factors including phosphatidylserine-dependent anti-prothrombin antibody, we failed to detect any responsible thrombogenic factors for this case of LV. Recently, diverse thrombogenic factors have been reported to be involved in LV. This case may suggest that unknown thrombogenic factors are additionally related to LV pathogenesis.
引用
收藏
页码:94 / 97
页数:4
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