Multisystem inflammatory syndrome in adults: A rare sequela of SARS-CoV-2 infection

被引：25

作者：

Ahmad, Faran ^{[1
]}

Ahmed, Arslan ^{[1
]}

Rajendraprasad, Sanu S. ^{[1
]}

Loranger, Austin ^{[1
]}

Gupta, Sonia ^{[1
]}

Velagapudi, Manasa ^{[1
]}

Vivekanandan, Renuga ^{[1
,2
,3
]}

Nahas, Joseph A. ^{[1
]}

Plambeck, Robert ^{[1
]}

Moore, Douglas ^{[1
]}

机构：

[1] Creighton Univ Med Ctr Bergan Mercy, 7500 Mercy Rd, Omaha, NE 68124 USA

[2] Creighton Univ, Sch Med, Omaha, NE 68124 USA

[3] Dr CC & Mabel L Criss Hlth Sci Complex 2, Omaha, NE 68178 USA

来源：

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES | 2021年 / 108卷

关键词：

SARS-CoV-2; infection; COVID-19; Multisystem inflammatory syndrome in adults (MIS-A);

D O I：

10.1016/j.ijid.2021.05.050

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Multisystem inflammatory syndrome in adults (MIS-A) came to attention back in June 2020, when the United States Center for Disease Control and Prevention (CDC) received initial reports regarding patients who had presented delayed and multisystem involvement of the disease, with clinical course resembling multisystem inflammatory syndrome in children (MIS-C). This study introduces a case of MIS-A, where the patient presented 3 weeks after initial COVID-19 exposure. His clinical course was consistent with the working definition of MIS-A as specified by the CDC. Aggressive supportive care in the intensive care unit, utilization of advanced heart failure devices, and immunomodulatory therapeutics (high-dose steroids, anakinra, intravenous immunoglobulin) led to clinical recovery. Management of MIS-A is a topic of ongoing research and needs more studies to elaborate on treatment modalities and clinical predictors. (c) 2021 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-ncnd/4.0/).

引用

页码：209 / 211

页数：3

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