Visible-Light-Driven Intermolecular Reductive Ene-Yne Coupling by Iridium/Cobalt Dual Catalysis for C(sp3)-C(sp2) Bond Formation

被引：19

作者：

Gonzalez, Maria J. ^{[1
]}

Breit, Bernhard ^{[1
]}

机构：

[1] Albert Ludwigs Univ Freiburg, Inst Organ Chem, Albertstr 21, D-79104 Freiburg, Germany

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2019年 / 25卷 / 69期

关键词：

alkynes; cobalt; dual catalysis; photoredox; reductive coupling; PHOTOREDOX CATALYSIS; COBALT CATALYSIS; HANTZSCH ESTERS; CARBON-CARBON; ALKYNES; 4-ALKYL-1,4-DIHYDROPYRIDINES; CYCLIZATIONS; COMPLEXES; ALDEHYDES; REAGENTS;

D O I：

10.1002/chem.201903708

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new methodology to form C(sp(3))-C(sp(2)) bonds by visible-light-driven intermolecular reductive ene-yne coupling has been successfully developed. The process relies on the ability of the Hantzsch ester to contribute in both SET and HAT processes through a unified cobalt and iridium catalytic system. This procedure avoids the use of stoichiometric amounts of reducing metallic reagents, which is translated into high functional-group tolerance and atom economy.

引用

页码：15746 / 15750

页数：5

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