HTLV-1 infections

被引:94
|
作者
Bangham, CRM [1 ]
机构
[1] Imperial Coll Sch Med, Dept Immunol, London W2 1PG, England
关键词
human T lymphotropic virus type 1; adult T cell leukaemia/lymphoma; tropical spastic paraparesis; myelopathy;
D O I
10.1136/jcp.53.8.581
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Human T lymphotropic virus type 1 (HTLV-1) causes disabling and fatal diseases, yet there is no vaccine, no satisfactory treatment, and no means of assessing the risk of disease or prognosis in infected people. Recent research on the molecular virology and immunology of HTLV-1 shows the importance of the host's immune response in reducing the risk of these diseases, and is beginning to explain why some HTLV-1 infected people develop serious illnesses whereas most remain healthy life long carriers of the virus. These findings might be applicable to other persistent virus infections such as human immunodeficiency virus, hepatitis B, and hepatitis C.
引用
收藏
页码:581 / 586
页数:6
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