Fabrication of poly (vinyl alcohol)/ovalbumin/cellulose nanocrystals/nanohydroxyapatite based biocomposite scaffolds

被引：18

作者：

Kumar, Anuj ^{[1
]}

Negi, Yuvraj Singh ^{[1
]}

Choudhary, Veena ^{[2
]}

Bhardwaj, Nishi Kant ^{[3
]}

机构：

[1] Indian Inst Technol Roorkee, Dept Polymer & Proc Engn, Roorkee 247667, Uttar Pradesh, India

[2] Indian Inst Technol, Ctr Polymer Sci & Engn, New Delhi, India

[3] Avantha Ctr Ind Res & Dev, Yamunanagar, Haryana, India

来源：

INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS | 2016年 / 65卷 / 04期

关键词：

Cellulose nanocrystals; freeze drying; nanohydroxyapatite; ovalbumin; PVA; scaffolds; IN-VITRO; MECHANICAL-PROPERTIES; HYDROXYAPATITE; OVALBUMIN; BONE; CELLULOSE; BIOCOMPATIBILITY; NANOCRYSTALS; COMPOSITES; BEHAVIOR;

D O I：

10.1080/00914037.2015.1099102

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Biocomposite scaffolds composed of PVA, ovalbumin, cellulose nanocrystals, and nanohydroxyapatite were fabricated by freeze-drying method. The results revealed that the different fractions of nanohydroxyapatite and cellulose nanocrystals provide the mechanical strength and stiffness to the desired biocomposite scaffolds. In vitro biomineralization showed the formation of apatite onto the surface of obtained biocomposite scaffolds and increased as amount of nanohydroxyapatite increased. The obtained results suggest that the different combinations of these four biomaterials can be used to fabricate highly porous scaffolds with desired mechanical performance and degradation rate by adjusting ratio for potential use in low load-bearing applications.

引用

页码：191 / 201

页数：11

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