Identification of tumour-associated T-CELL epitopes for vaccine development

被引：98

作者：

Stevanovic, S ^{[1
]}

机构：

[1] Univ Tubingen, Inst Cell Biol, Dept Immunol, D-72076 Tubingen, Germany

来源：

NATURE REVIEWS CANCER | 2002年 / 2卷 / 07期

关键词：

D O I：

10.1038/nrc841

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Ten years ago, the first melanoma patient was successfully treated by vaccination with a short peptide, which was, in fact, the first tumour-specific T-cell epitope ever defined - MAGE. Since then, a number of clinical vaccination studies have underlined the potential of tumour-specific T-cell epitopes. But, how can we identify more epitopes to improve their efficacy as an anticancer treatment?.

引用

页码：514 / 520

页数：7

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