Glycosidic flavonoids as rat-liver injury preventing compounds from green tea

被引：31

作者：

Wada, S ^{[1
]}

He, PM ^{[1
]}

Hashimoto, I ^{[1
]}

Watanabe, N ^{[1
]}

Sugiyama, K ^{[1
]}

机构：

[1] Shizuoka Univ, Fac Agr, Dept Appl Biol Chem, Shizuoka 4228529, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2000年 / 64卷 / 10期

关键词：

green tea; flavonoids; liver injury; D-galactosamine;

D O I：

10.1271/bbb.64.2262

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A glycosidic flavonoids-rich fraction from green tea leaves was purified to isolate Eve glycosidic flavonoids, guided by the detection of a preventive effect on D-galactosamine-induced liver injury in rats. These were identified as a flavone C-glycoside (1) and trisaccharide flavonols (25) based on the spectroscopic analyses. These compounds suppressed the D-galactosamine-induced increase of plasma alanine aminotransferase and asparatate aminotransferase activities in rats.

引用

页码：2262 / 2265

页数：4

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