Coronary artery aneurysms, insights from the international coronary artery aneurysm registry (CAAR)

被引：63

作者：

Nunez-Gil, Ivan J. ^{[1
,31
]}

Cerrato, Enrico ^{[2
]}

Bollati, Mario ^{[32
]}

Nombela-Franco, Luis ^{[1
]}

Terol, Belen ^{[33
]}

Alfonso-Rodriguez, Emilio ^{[3
,25
]}

Camacho Freire, Santiago J. ^{[4
,26
]}

Villablanca, Pedro A. ^{[5
]}

Amat Santos, Ignacio J. ^{[6
,27
]}

de la Torre Hernandez, Jose M. ^{[34
]}

Pascual, Isaac ^{[28
,29
,30
]}

Liebetrau, Christoph ^{[8
,9
]}

Camacho, Benjamin ^{[35
]}

Pavani, Marco ^{[22
]}

Albistur, Juan ^{[10
]}

Adriano Latini, Roberto ^{[36
]}

Varbella, Ferdinando ^{[2
]}

Alfonso Jimenez-Diaz, Victor ^{[12
]}

Piraino, Davide ^{[13
,17
]}

Mancone, Massimo ^{[14
]}

Alfonso, Fernando ^{[15
]}

Antonio Linares, Jose ^{[37
]}

Rodriguez-Olivares, Ramon ^{[16
]}

Jimenez Mazuecos, Jesus M. ^{[17
]}

Palazuelos Molinero, Jorge ^{[18
]}

Sanchez-Grande Flecha, Alejandro ^{[19
]}

Antoni Gomez-Hospital, Joan ^{[20
]}

Ielasi, Alfonso ^{[21
]}

Lozano, Inigo ^{[38
]}

Omede, Pierluigi ^{[22
]}

Bagur, Rodrigo ^{[39
]}

Ugo, Fabrizio ^{[23
]}

Medda, Massimo ^{[24
]}

Louka, Boshra F. ^{[25
]}

Kala, Petr ^{[40
]}

Escaned, Javier ^{[1
,31
]}

Bautista, Daniel ^{[41
]}

Feltes, Gisela ^{[1
]}

Salinas, Pablo ^{[1
]}

Alkhouli, Mohamad ^{[27
]}

Macaya, Carlos ^{[1
,31
]}

Fernandez-Ortiz, Antonio ^{[1
,31
,42
]}

Martinez Benitez, Piter ^{[3
]}

Gomez Menchero, Antonio ^{[4
]}

Leon Jimenez, Javier ^{[4
]}

Diaz Fernandez, Jose Francisco ^{[4
]}

Makkiya, Mohammed ^{[5
]}

Bulcha, Nurilign ^{[5
]}

Suri, Sarabjeet ^{[5
]}

机构：

[1] Hosp Clin San Carlos, Cardiovasc Inst, Avda Prof Martin Lagos S-N, Madrid 28040, Spain

[2] Infermi Hosp, Intervent Cardiol, Turin, Italy

[3] Inst Cardiol & Cirugia Cardiovasc, Havana, Cuba

[4] Hosp Juan Ramon Jimenez, Intervent Cardiol, Huelva, Spain

[5] Albert Einstein Coll Med, Montefiore Med Ctr, Intervent Cardiol, New York, NY USA

[6] Hosp Clin Univ Valladolid, Intervent Cardiol, CIBERCV, Valladolid, Spain

[7] Hosp Valdecilla, Cardiol Dept, Santander, Spain

[8] Kerckhoff Heart & Thorax Ctr, Dept Cardiol, Bad Nauheim, Germany

[9] DZHK German Ctr Cardiovasc Res, Partner Site Rhein Main, Frankfurt, Germany

[10] Hosp Clin Dr, Cardiol, Montevideo, Uruguay

[11] Osped Fatebenefratelli, Cardiol Dept, Milan, Italy

[12] Hosp Alvaro Cunqueiro, Intervent Cardiol, Vigo, Spain

[13] Azienda Osped Univ Policlin P Giaccone, UO Cardiol Interventist & Emodinam, Palermo, Italy

[14] Policlin Umberto 1, Sapienza Univ Rome, Dept Cardiovasc Resp Neurol Anaesthesiol & Geriat, Rome, Italy

[15] Hosp Univ La Princesa, Cardiol Dept, Madrid, Spain

[16] Utrecht Med Ctr, Intervent Cardiol, Utrecht, Netherlands

[17] H Gen Univ Albacete, Intervent Cardiol, Albacete, Spain

[18] Hosp Cent Def Gomez Ulla, Intervent Cardiol, Madrid, Spain

[19] H Univ Canarias, Intervent Cardiol, San Cristobal La Laguna, Spain

[20] Hosp Bellvitge Princeps Espanya, Intervent Cardiol, Barcelona, Spain

[21] Bolognini Hosp Seriate, Div Cardiol, ASST Bergamo Est, Seriate, Italy

[22] Citta Salute & Sci, Cardiol, Molinnette 1, Turin, Italy

[23] H San Giovanni Basco, Intervent Cardiol, Turin, Italy

[24] Ist Clin St Ambrogio, Intervent Cardiol Unit, Milan, Italy

[25] Mayo Clin Arizona, Div Cardiovasc Dis, Scottsdale, AZ USA

[26] Univ Hosp Brno, Dept Internal Med & Cardiol, Brno, Czech Republic

[27] West Virginia Univ, Cardiol, Inst Heart & Vasc, Morgantown, WV 26506 USA

[28] Hosp Univ Cent Asturias, Dept Cardiol, Oviedo, Spain

[29] ISPA, Inst Invest Sanitaria Principado Asturias, Oviedo, Spain

[30] Univ Oviedo, Oviedo, Spain

[31] Univ Complutense Madrid, Fac Med, Madrid, Spain

[32] Policlin San Donato, Intervent Cardiol, Milan, Italy

[33] Hosp Severo Ochoa, Dept Cardiol, Leganes, Spain

[34] IDIVAL, Hosp U Marques Valdecilla, Dept Cardiol, Santander, Spain

[35] Hosp Arnau Vilanova, Intervent Cardiol, Lerida, Spain

[36] ASST Fatebenefratelli Sacco, Cardiol Interventist, Milan, Italy

[37] H Lozano Blesa, Intervent Cardiol, Zaragoza, Spain

[38] Hosp Cabuenes, Intervent Cardiol, Gijon, Spain

[39] Univ Hosp, London Hlth Sci Ctr, Intervent Cardiol, London, ON, Canada

[40] Masaryk Univ, Fac Med, Brno, Czech Republic

[41] Inst Dominicano Cardiol, Cardiol, Santo Domingo, Dominican Rep

[42] CNIC, Madrid, Spain

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2020年 / 299卷

关键词：

INTRAVASCULAR ULTRASOUND; ELUTING STENT; IMPLANTATION;

D O I：

10.1016/j.ijcard.2019.05.067

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Coronary Aneurysms are a focal dilatation of an artery segment >1.5-fold the normal size of adjacent segments. Although some series have suggested a prevalence of 0.3-12%, data are lacking. In addition, they are not mentioned in practice guidelines. Our aim was investigate its prevalence, management and long-term outcomes. Methods and results: The coronary artery aneurysm registry (CAAR) involved 32 hospitals across 9 countries in America and Europe. We reviewed 436,467 consecutive angiograms performed over the period 2004-2016. Finally, 1565 patients were recruited. Aneurysm global prevalence was 0.35%. Most patients were male (78.5%) with a mean age of 65 years and frequent cardiovascular risk factors. The main indication for angiogram was an acute coronary syndrome, 966 cases. The number of aneurisms was <= 2 per patient in 95.8% of the cases, mostly saccular, most frequently found in the left anterior descending and with numbers proportional with coronary stenosis. Aortopathies were related with more aneurysms too. Most patients received any revascularization procedure (69%), commonly percutaneous (53%). After a median follow-up of 37.2 months, 485 suffered a combined event (MACE) and 240 died. Without major differences comparing CABG vs PCI, MACE and death were more frequent in patients who received bare metal stents. Conclusions: Coronary artery aneurysms are not uncommon. Usually, they are associated with coronary stenosis and high cardiovascular risk. Antiplatelet therapy seems reasonable and a percutaneous approach is safe and effective. (C) 2019 Elsevier B.V. All rights reserved.

引用

页码：49 / 55

页数：7

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